Jon Clardy

Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Publications

Neoconcinndiol hydroperoxide, a novel marine diterpenoid from the red alga Laurencia.

Authors: Authors: Howard BM, Fenical W, Finer J, Hirotsu K, Clardy J.
J Am Chem Soc 1977-09-14
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Letter: structure of cytochalasin E, a toxic metabolite of Aspergillus clavatus.

Authors: Authors: Büchi G, Kitaura Y, Yuan SS, Wright HE, Clardy J, Demain AL, Ginsukon T, Hunt N, Wogan GN.
J Am Chem Soc 1973-08-08
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Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways.

Authors: Authors: Ye L, Bae M, Cassilly CD, Jabba SV, Thorpe DW, Martin AM, Lu HY, Wang J, Thompson JD, Lickwar CR, Poss KD, Keating DJ, Jordt SE, Clardy J, Liddle RA, Rawls JF.
Cell Host Microbe 2021-02-10
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Tiny crystals have big potential for determining structures of small molecules.

Authors: Authors: Brown A, Clardy J.
Nature 2018-12-01
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Tryptorubin A: A Polycyclic Peptide from a Fungus-Derived Streptomycete.

Authors: Authors: Wyche TP, Ruzzini AC, Schwab L, Currie CR, Clardy J.
J Am Chem Soc 2017-09-20
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Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.

Authors: Authors: Vafai SB, Mevers E, Higgins KW, Fomina Y, Zhang J, Mandinova A, Newman D, Shaw SY, Clardy J, Mootha VK.
PLoS One 2016-01-01
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Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.

Authors: Authors: Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J.
J Nat Prod 2015-10-23
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Identification of protein kinase C activation as a novel mechanism for RGS2 protein upregulation through phenotypic screening of natural product extracts.

Authors: Authors: Raveh A, Schultz PJ, Aschermann L, Carpenter C, Tamayo-Castillo G, Cao S, Clardy J, Neubig RR, Sherman DH, Sjögren B.
Mol Pharmacol 2014-10-01
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X-ray crystallography: One size fits most.

Authors: Authors: Stallforth P, Clardy J.
Nature 2013-03-28
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Small molecule perimeter defense in entomopathogenic bacteria.

Authors: Authors: Crawford JM, Portmann C, Zhang X, Roeffaers MB, Clardy J.
Proc Natl Acad Sci U S A 2012-07-03
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