Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Fluoroprostaglandins: synthesis and biological evaluation of the methyl esters of (+)-12-fluoro-, (-)-ent-12-fluoro-, (+)-15-epi-fluoro-, and (-)-ent-15 epi-12-fluoroprostaglandin F2 alpha.
Authors: Authors: Grieco PA, Owens W, Wang CL, Williams E, Schillinger WJ, Hirotsu K, Clardy J.
J Med Chem
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Oppositol, a brominated sesquiterpene alcohol of a new skeletal class from the red alga, Laurencia subopposita.
Authors: Authors: Hall SS, Faulkner DJ, Fayos J, Clardy J.
J Am Chem Soc
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Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens.
Authors: Authors: Jackson DR, Cassilly CD, Plichta DR, Vlamakis H, Liu H, Melville SB, Xavier RJ, Clardy J.
ACS Chem Biol
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Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Authors: Authors: Kearney SE, Zahoránszky-Kohalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.
ACS Cent Sci
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Absolute Configurations of Griseorhodins A and C.
Authors: Authors: Ortega HE, Batista JM, Melo WGP, Clardy J, Pupo MT.
Tetrahedron Lett
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Homodimericin A: A Complex Hexacyclic Fungal Metabolite.
Authors: Authors: Mevers E, Saurí J, Liu Y, Moser A, Ramadhar TR, Varlan M, Williamson RT, Martin GE, Clardy J.
J Am Chem Soc
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A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.
Authors: Authors: Van Arnam EB, Ruzzini AC, Sit CS, Currie CR, Clardy J.
J Am Chem Soc
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Chemical interrogation of the malaria kinome.
Authors: Authors: Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J.
Chembiochem
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Identification of anziaic acid, a lichen depside from Hypotrachyna sp., as a new topoisomerase poison inhibitor.
Authors: Authors: Cheng B, Cao S, Vasquez V, Annamalai T, Tamayo-Castillo G, Clardy J, Tse-Dinh YC.
PLoS One
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A Bacillus subtilis sensor kinase involved in triggering biofilm formation on the roots of tomato plants.
Authors: Authors: Chen Y, Cao S, Chai Y, Clardy J, Kolter R, Guo JH, Losick R.
Mol Microbiol
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