Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Megathyrin B: a cytotoxic diterpene from Isodon megathyrsus.
Authors: Authors: Qiu SX, Sun HD, Lobkovsky E, Chai H, Clardy J, Farnsworth NR, Pezzuto JM, Fong HH.
Planta Med
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Structure of the spiroketal-macrolide ossamycin.
Authors: Authors: Kirst HA, Mynderse JS, Martin JW, Baker PJ, Paschal JW, Rios Steiner JL, Lobkovsky E, Clardy J.
J Antibiot (Tokyo)
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Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.
Authors: Authors: Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J.
Science
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Bipolaroxin, a selective phytotoxin produced by Bipolaris cynodontis.
Authors: Authors: Sugawara F, Strobel G, Fisher LE, Van Duyne GD, Clardy J.
Proc Natl Acad Sci U S A
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Letter: The structure of saxitoxin.
Authors: Authors: Schantz EJ, Ghazarossian VE, Schnoes HK, Strong FM, Springer JP, Pezzanite JO, Clardy J.
J Am Chem Soc
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Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering.
Authors: Authors: Helfrich EJN, Lin GM, Voigt CA, Clardy J.
Beilstein J Org Chem
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Defense contracts: molecular protection in insect-microbe symbioses.
Authors: Authors: Van Arnam EB, Currie CR, Clardy J.
Chem Soc Rev
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Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39.
Authors: Authors: Beemelmanns C, Ramadhar TR, Kim KH, Klassen JL, Cao S, Wyche TP, Hou Y, Poulsen M, Bugni TS, Currie CR, Clardy J.
Org Lett
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A New Diketopiperazine, Cyclo(D-trans-Hyp-L-Leu) from a Kenyan Bacterium Bacillus licheniformis LB 8CT.
Authors: Authors: Lee SR, Beemelmanns C, Tsuma LM, Clardy J, Cao S, Kim KH.
Nat Prod Commun
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The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Authors: Authors: Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R.
Sci Transl Med
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