Jonathan Abraham, MD

Assistant Professor of Microbiology, Harvard Medical School
Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity.
Authors: Authors: Koma T, Huang C, Coscia A, Hallam S, Manning JT, Maruyama J, Walker AG, Miller M, Smith JN, Patterson M, Abraham J, Paessler S.
PLoS Pathog
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Antibody-based inhibition of pathogenic New World Hemorrhagic Fever mammarenaviruses by steric occlusion of the human transferrin receptor 1 apical domain.
Authors: Authors: Ferrero S, Flores MD, Short C, Vazquez CA, Clark LE, Ziegenbein J, Zink S, Fuentes D, Payes C, Batto MV, Collazo M, García CC, Abraham J, Cordo SM, Rodriguez JA, Helguera G.
J Virol
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Transferrin receptor targeting by de novo sheet extension.
Authors: Authors: Sahtoe DD, Coscia A, Mustafaoglu N, Miller LM, Olal D, Vulovic I, Yu TY, Goreshnik I, Lin YR, Clark L, Busch F, Stewart L, Wysocki VH, Ingber DE, Abraham J, Baker D.
Proc Natl Acad Sci U S A
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SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms.
Authors: Authors: Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Brusic V, Choudhary MC, Regan J, Li JZ, Griffiths A, Abraham J.
Cell
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Audio Interview: The Implications of Changes in the Structural Biology of SARS-CoV-2.
Authors: Authors: Rubin EJ, Baden LR, Abraham J, Morrissey S.
N Engl J Med
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Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.
Authors: Authors: Clark SA, Clark LE, Pan J, Coscia A, McKay LGA, Shankar S, Johnson RI, Griffiths A, Abraham J.
bioRxiv
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Passive antibody therapy in COVID-19.
Authors: Authors: Abraham J.
Nat Rev Immunol
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An antibody recognizing the apical domain of human transferrin receptor 1 efficiently inhibits the entry of all new world hemorrhagic Fever arenaviruses.
Authors: Authors: Helguera G, Jemielity S, Abraham J, Cordo SM, Martinez MG, Rodríguez JA, Bregni C, Wang JJ, Farzan M, Penichet ML, Candurra NA, Choe H.
J Virol
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Transferrin receptor 1 in the zoonosis and pathogenesis of New World hemorrhagic fever arenaviruses.
Authors: Authors: Choe H, Jemielity S, Abraham J, Radoshitzky SR, Farzan M.
Curr Opin Microbiol
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Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses.
Authors: Authors: Abraham J, Corbett KD, Farzan M, Choe H, Harrison SC.
Nat Struct Mol Biol
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