Junying Yuan, PhD
Elizabeth D. Hay Professor of Cell Biology, Harvard Medical School
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Authors: Authors: Yoo LI, Liu DW, Le Vu S, Bronson RT, Wu H, Yuan J.
Cancer Res
View full abstract on Pubmed
Cancer Res
View full abstract on Pubmed
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.
Authors: Authors: Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB.
J Cell Biol
View full abstract on Pubmed
J Cell Biol
View full abstract on Pubmed
Inducing autophagy harmlessly.
Structure-activity relationship study of novel necroptosis inhibitors.
Authors: Authors: Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD.
Bioorg Med Chem Lett
View full abstract on Pubmed
Bioorg Med Chem Lett
View full abstract on Pubmed
Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis.
c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1.
Authors: Authors: Xu L, Zhu J, Hu X, Zhu H, Kim HT, LaBaer J, Goldberg A, Yuan J.
Mol Cell
View full abstract on Pubmed
Mol Cell
View full abstract on Pubmed
A cellular response to an internal energy crisis.
Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.
To kill or to arrest: that is the new question for Apaf-1.
Modification of protein sub-nuclear localization by synthetic phosphoinositides: evidence for nuclear phosphoinositide signaling mechanisms.
Authors: Authors: Gozani O, Field SJ, Ferguson CG, Ewalt M, Mahlke C, Cantley LC, Prestwich GD, Yuan J.
Adv Enzyme Regul
View full abstract on Pubmed
Adv Enzyme Regul
View full abstract on Pubmed