Karen Adelman, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals.
Authors: Authors: Henriques T, Gilchrist DA, Nechaev S, Bern M, Muse GW, Burkholder A, Fargo DC, Adelman K.
Mol Cell
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Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling.
Authors: Authors: Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Rogatsky I.
Proc Natl Acad Sci U S A
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Emerging Roles of Non-Coding RNA Transcription.
Authors: Authors: Kaikkonen MU, Adelman K.
Trends Biochem Sci
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Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle.
Authors: Authors: Gupte R, Muse GW, Chinenov Y, Adelman K, Rogatsky I.
Proc Natl Acad Sci U S A
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Spt6 enhances the elongation rate of RNA polymerase II in vivo.
Authors: Authors: Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT.
EMBO J
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Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster.
Authors: Authors: Meers MP, Adelman K, Duronio RJ, Strahl BD, McKay DJ, Matera AG.
BMC Genomics
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SnapShot: Transcription regulation: pausing.
Authors: Authors: Fromm G, Gilchrist DA, Adelman K.
Cell
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Using ChIP-chip and ChIP-seq to study the regulation of gene expression: genome-wide localization studies reveal widespread regulation of transcription elongation.
Authors: Authors: Gilchrist DA, Fargo DC, Adelman K.
Methods
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Widespread transcriptional pausing and elongation control at enhancers.
Authors: Authors: Henriques T, Scruggs BS, Inouye MO, Muse GW, Williams LH, Burkholder AB, Lavender CA, Fargo DC, Adelman K.
Genes Dev
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Catching the waves: following the leading edge of elongating RNA polymerase II.
Authors: Authors: Henriques T, Adelman K.
Mol Cell
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