Luk Vandenberghe, PhD
Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Adeno-associated virus: fit to serve.
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice.
Authors: Authors: Bell CL, Vandenberghe LH, Bell P, Limberis MP, Gao GP, Van Vliet K, Agbandje-McKenna M, Wilson JM.
J Clin Invest
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J Clin Invest
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Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses.
Authors: Authors: Calcedo R, Vandenberghe LH, Gao G, Lin J, Wilson JM.
J Infect Dis
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J Infect Dis
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CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes.
Authors: Authors: Parry RV, Rumbley CA, Vandenberghe LH, June CH, Riley JL.
J Immunol
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J Immunol
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AAV Engineering Identifies a Species Barrier That Highlights a Portal to the Brain.
Genome editing abrogates angiogenesis in vivo.
Authors: Authors: Huang X, Zhou G, Wu W, Duan Y, Ma G, Song J, Xiao R, Vandenberghe L, Zhang F, D'Amore PA, Lei H.
Nat Commun
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Nat Commun
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Promising and delivering gene therapies for vision loss.
Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs.
Authors: Authors: Bell P, Gao G, Haskins ME, Wang L, Sleeper M, Wang H, Calcedo R, Vandenberghe LH, Chen SJ, Weisse C, Withnall E, Wilson JM.
Hum Gene Ther
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Hum Gene Ther
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Host immune responses to chronic adenovirus infections in human and nonhuman primates.
Authors: Authors: Calcedo R, Vandenberghe LH, Roy S, Somanathan S, Wang L, Wilson JM.
J Virol
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J Virol
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Adeno-associated viruses undergo substantial evolution in primates during natural infections.
Authors: Authors: Gao G, Alvira MR, Somanathan S, Lu Y, Vandenberghe LH, Rux JJ, Calcedo R, Sanmiguel J, Abbas Z, Wilson JM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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