Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector.
Authors: Authors: Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, Shah S, Shelke R, Maurer AC, Plovie E, Xiao R, Vandenberghe LH.
Cell Rep
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Novel adeno-associated viral vectors for retinal gene therapy.
Authors: Authors: Vandenberghe LH, Auricchio A.
Gene Ther
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Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver.
Authors: Authors: Breous E, Somanathan S, Vandenberghe LH, Wilson JM.
Hepatology
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New recombinant serotypes of AAV vectors.
Authors: Authors: Gao G, Vandenberghe LH, Wilson JM.
Curr Gene Ther
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Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries.
Authors: Authors: Schmit PF, Pacouret S, Zinn E, Telford E, Nicolaou F, Broucque F, Andres-Mateos E, Xiao R, Penaud-Budloo M, Bouzelha M, Jaulin N, Adjali O, Ayuso E, Vandenberghe LH.
Mol Ther Methods Clin Dev
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An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor.
Authors: Authors: Dudek AM, Pillay S, Puschnik AS, Nagamine CM, Cheng F, Qiu J, Carette JE, Vandenberghe LH.
J Virol
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What Is Next for Retinal Gene Therapy?
Authors: Authors: Vandenberghe LH.
Cold Spring Harb Perspect Med
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Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model.
Authors: Authors: Aleman TS, Cideciyan AV, Aguirre GK, Huang WC, Mullins CL, Roman AJ, Sumaroka A, Olivares MB, Tsai FF, Schwartz SB, Vandenberghe LH, Limberis MP, Stone EM, Bell P, Wilson JM, Jacobson SG.
Invest Ophthalmol Vis Sci
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Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates.
Authors: Authors: Roy S, Vandenberghe LH, Kryazhimskiy S, Grant R, Calcedo R, Yuan X, Keough M, Sandhu A, Wang Q, Medina-Jaszek CA, Plotkin JB, Wilson JM.
PLoS Pathog
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Complete nucleotide sequences and genome organization of four chimpanzee adenoviruses.
Authors: Authors: Roy S, Gao G, Clawson DS, Vandenberghe LH, Farina SF, Wilson JM.
Virology
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