Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.
Authors: Authors: Cronin T, Vandenberghe LH, Hantz P, Juttner J, Reimann A, Kacsó AE, Huckfeldt RM, Busskamp V, Kohler H, Lagali PS, Roska B, Bennett J.
EMBO Mol Med
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Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques.
Authors: Authors: Kassim SH, Vandenberghe LH, Hovhannisyan R, Wilson JM, Rader DJ.
Physiol Genomics
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Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.
Authors: Authors: Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG.
Hum Gene Ther
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Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.
Authors: Authors: Simmons G, Rennekamp AJ, Chai N, Vandenberghe LH, Riley JL, Bates P.
J Virol
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In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Authors: Authors: Goldstein JM, Tabebordbar M, Zhu K, Wang LD, Messemer KA, Peacker B, Ashrafi Kakhki S, Gonzalez-Celeiro M, Shwartz Y, Cheng JKW, Xiao R, Barungi T, Albright C, Hsu YC, Vandenberghe LH, Wagers AJ.
Cell Rep
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Single stranded adeno-associated virus achieves efficient gene transfer to anterior segment in the mouse eye.
Authors: Authors: Wang L, Xiao R, Andres-Mateos E, Vandenberghe LH.
PLoS One
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Adeno-associated virus: fit to serve.
Authors: Authors: Zinn E, Vandenberghe LH.
Curr Opin Virol
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The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice.
Authors: Authors: Bell CL, Vandenberghe LH, Bell P, Limberis MP, Gao GP, Van Vliet K, Agbandje-McKenna M, Wilson JM.
J Clin Invest
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Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses.
Authors: Authors: Calcedo R, Vandenberghe LH, Gao G, Lin J, Wilson JM.
J Infect Dis
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CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes.
Authors: Authors: Parry RV, Rumbley CA, Vandenberghe LH, June CH, Riley JL.
J Immunol
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