Luk Vandenberghe, PhD

Associate Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Delivery of Adeno-Associated Virus Vectors in Adult Mammalian Inner-Ear Cell Subtypes Without Auditory Dysfunction.
Authors: Authors: Tao Y, Huang M, Shu Y, Ruprecht A, Wang H, Tang Y, Vandenberghe LH, Wang Q, Gao G, Kong WJ, Chen ZY.
Hum Gene Ther
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Perspectives on best practices for gene therapy programs.
Authors: Authors: Cheever TR, Berkley D, Braun S, Brown RH, Byrne BJ, Chamberlain JS, Cwik V, Duan D, Federoff HJ, High KA, Kaspar BK, Klinger KW, Larkindale J, Lincecum J, Mavilio F, McDonald CL, McLaughlin J, Weiss McLeod B, Mendell JR, Nuckolls G, Stedman HH, Tagle DA, Vandenberghe LH, Wang H, Wernett PJ, Wilson JM, Porter JD, Gubitz AK.
Hum Gene Ther
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Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey.
Authors: Authors: Vandenberghe LH, Bell P, Maguire AM, Cearley CN, Xiao R, Calcedo R, Wang L, Castle MJ, Maguire AC, Grant R, Wolfe JH, Wilson JM, Bennett J.
Sci Transl Med
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Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.
Authors: Authors: Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM.
J Immunol
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Clades of Adeno-associated viruses are widely disseminated in human tissues.
Authors: Authors: Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X, Wilson JM.
J Virol
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GPR108 Is a Highly Conserved AAV Entry Factor.
Authors: Authors: Dudek AM, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, Franceschini JS, Estelien R, Carette JE, Zhou GL, Vandenberghe LH.
Mol Ther
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Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting.
Authors: Authors: Carvalho LS, Turunen HT, Wassmer SJ, Luna-Velez MV, Xiao R, Bennett J, Vandenberghe LH.
Front Neurosci
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Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter.
Authors: Authors: Cronin T, Vandenberghe LH, Hantz P, Juttner J, Reimann A, Kacsó AE, Huckfeldt RM, Busskamp V, Kohler H, Lagali PS, Roska B, Bennett J.
EMBO Mol Med
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Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques.
Authors: Authors: Kassim SH, Vandenberghe LH, Hovhannisyan R, Wilson JM, Rader DJ.
Physiol Genomics
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Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.
Authors: Authors: Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG.
Hum Gene Ther
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