Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Structural basis for dynamic regulation of the human 26S proteasome.
Authors: Authors: Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y.
Proc Natl Acad Sci U S A
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On a possible evolutionary link of the stomochord of hemichordates to pharyngeal organs of chordates.
Authors: Authors: Satoh N, Tagawa K, Lowe CJ, Yu JK, Kawashima T, Takahashi H, Ogasawara M, Kirschner M, Hisata K, Su YH, Gerhart J.
Genesis
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Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex.
Authors: Authors: Wang W, Kirschner MW.
Nat Cell Biol
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Fifty years after Jacob and Monod: what are the unanswered questions in molecular biology?
Authors: Authors: Kirschner MW, Shapiro L, McAdams H, Almouzni G, Sharp PA, Young RA, Alon U.
Mol Cell
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UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex.
Authors: Authors: Wu T, Merbl Y, Huo Y, Gallop JL, Tzur A, Kirschner MW.
Proc Natl Acad Sci U S A
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An actin-based wave generator organizes cell motility.
Authors: Authors: Weiner OD, Marganski WA, Wu LF, Altschuler SJ, Kirschner MW.
PLoS Biol
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Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.
Authors: Authors: Beddows S, Schülke N, Kirschner M, Barnes K, Franti M, Michael E, Ketas T, Sanders RW, Maddon PJ, Olson WC, Moore JP.
J Virol
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Hemichordate embryos: procurement, culture, and basic methods.
Authors: Authors: Lowe CJ, Tagawa K, Humphreys T, Kirschner M, Gerhart J.
Methods Cell Biol
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A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity.
Authors: Authors: Weiner OD, Neilsen PO, Prestwich GD, Kirschner MW, Cantley LC, Bourne HR.
Nat Cell Biol
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LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.
Authors: Authors: Feng Y, Olson EC, Stukenberg PT, Flanagan LA, Kirschner MW, Walsh CA.
Neuron
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