Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.
Authors: Authors: Gerhart J, Wu M, Kirschner M.
J Cell Biol
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A reinvestigation of the role of the grey crescent in axis formation in xenopus laevis.
Authors: Authors: Gerhart J, Ubbels G, Black S, Hara K, Kirschner M.
Nature
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Intracellular localization of the high molecular weight microtubule accessory protein by indirect immunofluorescence.
Authors: Authors: Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW.
J Cell Biol
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Microtubules from mammalian brain: some properties of their depolymerization products and a proposed mechanism of assembly and disassembly.
Authors: Authors: Kirschner MW, Williams RC, Weingarten M, Gerhart JC.
Proc Natl Acad Sci U S A
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SCIENTIFIC COMMUNITY. Preprints for the life sciences.
Authors: Authors: Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C.
Science
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Quantitative Lys-?-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.
Authors: Authors: Thompson JW, Nagel J, Hoving S, Gerrits B, Bauer A, Thomas JR, Kirschner MW, Schirle M, Luchansky SJ.
J Biol Chem
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Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions.
Authors: Authors: Cooper KL, Oh S, Sung Y, Dasari RR, Kirschner MW, Tabin CJ.
Nature
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ß-catenin specifies the endomesoderm and defines the posterior organizer of the hemichordate Saccoglossus kowalevskii.
Authors: Authors: Darras S, Gerhart J, Terasaki M, Kirschner M, Lowe CJ.
Development
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The incoherent feedforward loop can provide fold-change detection in gene regulation.
Authors: Authors: Goentoro L, Shoval O, Kirschner MW, Alon U.
Mol Cell
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Authors: Authors: Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.
Nature
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