Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Quantitative reconstitution of mitotic CDK1 activation in somatic cell extracts.
Authors: Authors: Deibler RW, Kirschner MW.
Mol Cell
View full abstract on Pubmed
The relationship between evolutionary and physiological variation in hemoglobin.
Authors: Authors: Milo R, Hou JH, Springer M, Brenner MP, Kirschner MW.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis.
Authors: Authors: Kwan KM, Kirschner MW.
Development
View full abstract on Pubmed
Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly.
Authors: Authors: Campellone KG, Rankin S, Pawson T, Kirschner MW, Tipper DJ, Leong JM.
J Cell Biol
View full abstract on Pubmed
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck.
Authors: Authors: Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW.
Nature
View full abstract on Pubmed
Pin1 acts catalytically to promote a conformational change in Cdc25.
Authors: Authors: Stukenberg PT, Kirschner MW.
Mol Cell
View full abstract on Pubmed
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis.
Authors: Authors: Zou H, McGarry TJ, Bernal T, Kirschner MW.
Science
View full abstract on Pubmed
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins.
Authors: Authors: Shen M, Stukenberg PT, Kirschner MW, Lu KP.
Genes Dev
View full abstract on Pubmed
Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation.
Authors: Authors: Lustig KD, Kroll KL, Sun EE, Kirschner MW.
Development
View full abstract on Pubmed
The role of microtubules in growth cone turning at substrate boundaries.
Authors: Authors: Tanaka E, Kirschner MW.
J Cell Biol
View full abstract on Pubmed