Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo.
Authors: Authors: Kirschner MW.
J Cell Biol
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Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin.
Authors: Authors: Cleveland DW, Hwo SY, Kirschner MW.
J Mol Biol
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Anteroposterior axis patterning by early canonical Wnt signaling during hemichordate development.
Authors: Authors: Darras S, Fritzenwanker JH, Uhlinger KR, Farrelly E, Pani AM, Hurley IA, Norris RP, Osovitz M, Terasaki M, Wu M, Aronowicz J, Kirschner M, Gerhart JC, Lowe CJ.
PLoS Biol
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On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development.
Authors: Authors: Peshkin L, Wühr M, Pearl E, Haas W, Freeman RM, Gerhart JC, Klein AM, Horb M, Gygi SP, Kirschner MW.
Dev Cell
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Rescuing US biomedical research from its systemic flaws.
Authors: Authors: Alberts B, Kirschner MW, Tilghman S, Varmus H.
Proc Natl Acad Sci U S A
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Identical genomic organization of two hemichordate hox clusters.
Authors: Authors: Freeman R, Ikuta T, Wu M, Koyanagi R, Kawashima T, Tagawa K, Humphreys T, Fang GC, Fujiyama A, Saiga H, Lowe C, Worley K, Jenkins J, Schmutz J, Kirschner M, Rokhsar D, Satoh N, Gerhart J.
Curr Biol
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Protein microarrays for genome-wide posttranslational modification analysis.
Authors: Authors: Merbl Y, Kirschner MW.
Wiley Interdiscip Rev Syst Biol Med
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The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus.
Authors: Authors: Jorgensen P, Steen JA, Steen H, Kirschner MW.
Development
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Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.
Authors: Authors: Weiner OD, Rentel MC, Ott A, Brown GE, Jedrychowski M, Yaffe MB, Gygi SP, Cantley LC, Bourne HR, Kirschner MW.
PLoS Biol
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Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality.
Authors: Authors: Margalit DN, Romberg L, Mets RB, Hebert AM, Mitchison TJ, Kirschner MW, RayChaudhuri D.
Proc Natl Acad Sci U S A
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