Marc Kirschner

Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School

Publications

APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction.

Authors: Authors: Wan L, Tan M, Yang J, Inuzuka H, Dai X, Wu T, Liu J, Shaik S, Chen G, Deng J, Malumbres M, Letai A, Kirschner MW, Sun Y, Wei W.
Dev Cell 2014-05-27
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Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster.

Authors: Authors: Wühr M, Haas W, McAlister GC, Peshkin L, Rad R, Kirschner MW, Gygi SP.
Anal Chem 2012-11-06
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Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression.

Authors: Authors: Wu S, Wang W, Kong X, Congdon LM, Yokomori K, Kirschner MW, Rice JC.
Genes Dev 2010-11-15
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Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.

Authors: Authors: Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, Kirschner M, Dyson N, Wei W.
Mol Biol Cell 2009-07-01
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Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.

Authors: Authors: Peterson JR, Lebensohn AM, Pelish HE, Kirschner MW.
Chem Biol 2006-04-01
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Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.

Authors: Authors: Rape M, Kirschner MW.
Nature 2004-12-02
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Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.

Authors: Authors: Ayad NG, Rankin S, Murakami M, Jebanathirajah J, Gygi S, Kirschner MW.
Cell 2003-04-04
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Molecular targets of vertebrate segmentation: two mechanisms control segmental expression of Xenopus hairy2 during somite formation.

Authors: Authors: Davis RL, Turner DL, Evans LM, Kirschner MW.
Dev Cell 2001-10-01
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Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts.

Authors: Authors: Salic A, Lee E, Mayer L, Kirschner MW.
Mol Cell 2000-03-01
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Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1.

Authors: Authors: Fang G, Yu H, Kirschner MW.
Mol Cell 1998-08-01
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