Marc Kirschner

Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School

Publications

Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation.

Authors: Authors: Lee HJ, Jedrychowski MP, Vinayagam A, Wu N, Shyh-Chang N, Hu Y, Min-Wen C, Moore JK, Asara JM, Lyssiotis CA, Perrimon N, Gygi SP, Cantley LC, Kirschner MW.
Cell Rep 2017-07-18
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Substrate degradation by the proteasome: a single-molecule kinetic analysis.

Authors: Authors: Lu Y, Lee BH, King RW, Finley D, Kirschner MW.
Science 2015-04-10
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Beyond Darwin: evolvability and the generation of novelty.

Authors: Authors: Kirschner M.
BMC Biol 2013-11-07
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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.

Authors: Authors: Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, Kafri R, Kirschner MW, Clish CB, Mootha VK.
Science 2012-05-25
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Using buoyant mass to measure the growth of single cells.

Authors: Authors: Godin M, Delgado FF, Son S, Grover WH, Bryan AK, Tzur A, Jorgensen P, Payer K, Grossman AD, Kirschner MW, Manalis SR.
Nat Methods 2010-05-01
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Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis.

Authors: Authors: Steen JA, Steen H, Georgi A, Parker K, Springer M, Kirchner M, Hamprecht F, Kirschner MW.
Proc Natl Acad Sci U S A 2008-04-22
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Characterization of a new qQq-FTICR mass spectrometer for post-translational modification analysis and top-down tandem mass spectrometry of whole proteins.

Authors: Authors: Jebanathirajah JA, Pittman JL, Thomson BA, Budnik BA, Kaur P, Rape M, Kirschner M, Costello CE, O'Connor PB.
J Am Soc Mass Spectrom 2005-12-01
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Purification and architecture of the ubiquitous Wave complex.

Authors: Authors: Gautreau A, Ho HY, Li J, Steen H, Gygi SP, Kirschner MW.
Proc Natl Acad Sci U S A 2004-03-30
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Anaphase specific auto-cleavage of separase.

Authors: Authors: Zou H, Stemman O, Anderson JS, Mann M, Kirschner MW.
FEBS Lett 2002-09-25
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Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1.

Authors: Authors: Pfleger CM, Salic A, Lee E, Kirschner MW.
Genes Dev 2001-07-15
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