Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Using buoyant mass to measure the growth of single cells.
Authors: Authors: Godin M, Delgado FF, Son S, Grover WH, Bryan AK, Tzur A, Jorgensen P, Payer K, Grossman AD, Kirschner MW, Manalis SR.
Nat Methods
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Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis.
Authors: Authors: Steen JA, Steen H, Georgi A, Parker K, Springer M, Kirchner M, Hamprecht F, Kirschner MW.
Proc Natl Acad Sci U S A
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Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements.
Authors: Authors: Steen H, Jebanathirajah JA, Rush J, Morrice N, Kirschner MW.
Mol Cell Proteomics
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Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.
Authors: Authors: Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG.
Nature
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Intracellular signal propagation in a two-dimensional autocatalytic reaction model.
Authors: Authors: Castiglione F, Bernaschi M, Succi S, Heinrich R, Kirschner MW.
Phys Rev E Stat Nonlin Soft Matter Phys
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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway.
Authors: Authors: Rohatgi R, Nollau P, Ho HY, Kirschner MW, Mayer BJ.
J Biol Chem
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Control of mitotic transitions by the anaphase-promoting complex.
Authors: Authors: Fang G, Yu H, Kirschner MW.
Philos Trans R Soc Lond B Biol Sci
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Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts.
Authors: Authors: Ma L, Cantley LC, Janmey PA, Kirschner MW.
J Cell Biol
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How proteolysis drives the cell cycle.
Authors: Authors: King RW, Deshaies RJ, Peters JM, Kirschner MW.
Science
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Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.
Authors: Authors: Deshaies RJ, Chau V, Kirschner M.
EMBO J
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