Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Authors: Authors: Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y.
Mol Cell
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Specificity of the anaphase-promoting complex: a single-molecule study.
Authors: Authors: Lu Y, Wang W, Kirschner MW.
Science
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Size homeostasis in adherent cells studied by synthetic phase microscopy.
Authors: Authors: Sung Y, Tzur A, Oh S, Choi W, Li V, Dasari RR, Yaqoob Z, Kirschner MW.
Proc Natl Acad Sci U S A
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ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
Authors: Authors: Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F.
Nature
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Need-based up-regulation of protein levels in response to deletion of their duplicate genes.
Authors: Authors: DeLuna A, Springer M, Kirschner MW, Kishony R.
PLoS Biol
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Profile: Bruce Alberts, Science's new editor.
Authors: Authors: Kirschner M.
Science
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Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements.
Authors: Authors: Steen H, Jebanathirajah JA, Rush J, Morrice N, Kirschner MW.
Mol Cell Proteomics
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Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.
Authors: Authors: Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG.
Nature
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Intracellular signal propagation in a two-dimensional autocatalytic reaction model.
Authors: Authors: Castiglione F, Bernaschi M, Succi S, Heinrich R, Kirschner MW.
Phys Rev E Stat Nonlin Soft Matter Phys
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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway.
Authors: Authors: Rohatgi R, Nollau P, Ho HY, Kirschner MW, Mayer BJ.
J Biol Chem
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