Marc Kirschner, PhD

John Franklin Enders University Professor of Systems Biology, Harvard Medical School
The incoherent feedforward loop can provide fold-change detection in gene regulation.
Authors: Authors: Goentoro L, Shoval O, Kirschner MW, Alon U.
Mol Cell
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
Authors: Authors: Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW, Elledge SJ.
Nature
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Domain structure of separase and its binding to securin as determined by EM.
Authors: Authors: Viadiu H, Stemmann O, Kirschner MW, Walz T.
Nat Struct Mol Biol
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WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility.
Authors: Authors: Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW.
EMBO J
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An approach to increased polyplex gene delivery by peptides selected from a phage display library.
Authors: Authors: Morpurgo M, Kirschner M, Radu A.
J Biochem Biophys Methods
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Transient expression and heat-stress-induced co-aggregation of endogenous and heterologous small heat-stress proteins in tobacco protoplasts.
Authors: Authors: Kirschner M, Winkelhaus S, Thierfelder JM, Nover L.
Plant J
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A visit to the Hubrecht laboratory.
Authors: Authors: Kirschner M.
Int J Dev Biol
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Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy.
Authors: Authors: Cryns VL, Byun Y, Rana A, Mellor H, Lustig KD, Ghanem L, Parker PJ, Kirschner MW, Yuan J.
J Biol Chem
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Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation.
Authors: Authors: Yu H, King RW, Peters JM, Kirschner MW.
Curr Biol
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The role of biomedical research in health care reform.
Authors: Authors: Kirschner MW, Marincola E, Teisberg EO.
Science
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