Nathanael Gray, PhD

Nancy Lurie Marks Professor of Biological Chemistry and Molecular Pharmacology in the Field of Medical Oncology, Dana-Farber Cancer Institute
Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation.
Authors: Authors: Wang A, Yan XE, Wu H, Wang W, Hu C, Chen C, Zhao Z, Zhao P, Li X, Wang L, Wang B, Ye Z, Wang J, Wang C, Zhang W, Gray NS, Weisberg EL, Chen L, Liu J, Yun CH, Liu Q.
Oncotarget
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Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair.
Authors: Authors: Udayakumar D, Pandita RK, Horikoshi N, Liu Y, Liu Q, Wong KK, Hunt CR, Gray NS, Minna JD, Pandita TK, Westover KD.
Radiat Res
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Corrigendum: The promise and peril of chemical probes.
Authors: Authors: Arrowsmith CH, Audia JE, Austin C, Baell J, Bennett J, Blagg J, Bountra C, Brennan PE, Brown PJ, Bunnage ME, Buser-Doepner C, Campbell RM, Carter AJ, Cohen P, Copeland RA, Cravatt B, Dahlin JL, Dhanak D, Edwards AM, Frederiksen M, Frye SV, Gray N, Grimshaw CE, Hepworth D, Howe T, Huber KV, Jin J, Knapp S, Kotz JD, Kruger RG, Lowe D, Mader MM, Marsden B, Mueller-Fahrnow A, Müller S, O'Hagan RC, Overington JP, Owen DR, Rosenberg SH, Ross R, Roth B, Schapira M, Schreiber SL, Shoichet B, Sundström M, Superti-Furga G, Taunton J, Toledo-Sherman L, Walpole C, Walters MA, Willson TM, Workman P, Young RN, Zuercher WJ.
Nat Chem Biol
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Suppression of interferon ß gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members.
Authors: Authors: Malik N, Vollmer S, Nanda SK, Lopez-Pelaez M, Prescott A, Gray N, Cohen P.
Biochem J
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A-770041 reverses paclitaxel and doxorubicin resistance in osteosarcoma cells.
Authors: Authors: Duan Z, Zhang J, Ye S, Shen J, Choy E, Cote G, Harmon D, Mankin H, Hua Y, Zhang Y, Gray NS, Hornicek FJ.
BMC Cancer
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Fluorescent visualization of Src by using dasatinib-BODIPY.
Authors: Authors: Vetter ML, Zhang Z, Liu S, Wang J, Cho H, Zhang J, Zhang W, Gray NS, Yang PL.
Chembiochem
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Digital pattern recognition-based image analysis quantifies immune infiltrates in distinct tissue regions of colorectal cancer and identifies a metastatic phenotype.
Authors: Authors: Angell HK, Gray N, Womack C, Pritchard DI, Wilkinson RW, Cumberbatch M.
Br J Cancer
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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
Authors: Authors: Sulahian R, Kwon JJ, Walsh KH, Pailler E, Bosse TL, Thaker M, Almanza D, Dempster JM, Pan J, Piccioni F, Dumont N, Gonzalez A, Rennhack J, Nabet B, Bachman JA, Goodale A, Lee Y, Bagul M, Liao R, Navarro A, Yuan TL, Ng RWS, Raghavan S, Gray NS, Tsherniak A, Vazquez F, Root DE, Firestone AJ, Settleman J, Hahn WC, Aguirre AJ.
Cell Rep
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Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6.
Authors: Authors: Jiang B, Wang ES, Donovan KA, Liang Y, Fischer ES, Zhang T, Gray NS.
Angew Chem Int Ed Engl
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A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.
Authors: Authors: Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C.
Nat Cell Biol
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