Nathanael Gray, PhD

Nancy Lurie Marks Professor of Biological Chemistry and Molecular Pharmacology in the Field of Medical Oncology, Dana-Farber Cancer Institute
Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.
Authors: Authors: Williams CA, Fernandez-Alonso R, Wang J, Toth R, Gray NS, Findlay GM.
Cell Rep
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Discovery of a Highly Potent and Selective Indenoindolone Type 1 Pan-FLT3 Inhibitor.
Authors: Authors: Hatcher JM, Weisberg E, Sim T, Stone RM, Liu S, Griffin JD, Gray NS.
ACS Med Chem Lett
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Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.
Authors: Authors: Wilhelmsen K, Xu F, Farrar K, Tran A, Khakpour S, Sundar S, Prakash A, Wang J, Gray NS, Hellman J.
Sci Signal
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Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor.
Authors: Authors: Christensen CL, Kwiatkowski N, Abraham BJ, Carretero J, Al-Shahrour F, Zhang T, Chipumuro E, Herter-Sprie GS, Akbay EA, Altabef A, Zhang J, Shimamura T, Capelletti M, Reibel JB, Cavanaugh JD, Gao P, Liu Y, Michaelsen SR, Poulsen HS, Aref AR, Barbie DA, Bradner JE, George RE, Gray NS, Young RA, Wong KK.
Cancer Cell
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Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.
Authors: Authors: Ritorto MS, Ewan R, Perez-Oliva AB, Knebel A, Buhrlage SJ, Wightman M, Kelly SM, Wood NT, Virdee S, Gray NS, Morrice NA, Alessi DR, Trost M.
Nat Commun
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Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling.
Authors: Authors: Codeluppi S, Fernandez-Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, Olson L, Gray NS, Svensson CI, Uhlén P.
PLoS One
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Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells.
Authors: Authors: Taipale M, Krykbaeva I, Whitesell L, Santagata S, Zhang J, Liu Q, Gray NS, Lindquist S.
Nat Biotechnol
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Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice.
Authors: Authors: Tang X, Drotar J, Li K, Clairmont CD, Brumm AS, Sullins AJ, Wu H, Liu XS, Wang J, Gray NS, Sur M, Jaenisch R.
Sci Transl Med
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Coordinating Tissue Regeneration Through Transforming Growth Factor-ß Activated Kinase 1 Inactivation and Reactivation.
Authors: Authors: Hsieh HHS, Agarwal S, Cholok DJ, Loder SJ, Kaneko K, Huber A, Chung MT, Ranganathan K, Habbouche J, Li J, Butts J, Reimer J, Kaura A, Drake J, Breuler C, Priest CR, Nguyen J, Brownley C, Peterson J, Ozgurel SU, Niknafs YS, Li S, Inagaki M, Scott G, Krebsbach PH, Longaker MT, Westover K, Gray N, Ninomiya-Tsuji J, Mishina Y, Levi B.
Stem Cells
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Discovery of Immunologically Inspired Small Molecules That Target the Viral Envelope Protein.
Authors: Authors: Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL.
ACS Infect Dis
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