Pamela Silver, PhD
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology, Harvard Medical School
mRNA nuclear export and human disease.
Transcriptional regulation at the nuclear pore complex.
Systems biology of gene regulation fulfills its promise.
A systems view of mRNP biology.
A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.
Authors: Authors: Hitchcock AL, Auld K, Gygi SP, Silver PA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling.
Authors: Authors: Valentini SR, Casolari JM, Oliveira CC, Silver PA, McBride AE.
Genetics
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Genetics
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7The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex.
Authors: Authors: Shen EC, Stage-Zimmermann T, Chui P, Silver PA.
J Biol Chem
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J Biol Chem
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Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation.
Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
Authors: Authors: Clarkson WD, Corbett AH, Paschal BM, Kent HM, McCoy AJ, Gerace L, Silver PA, Stewart M.
J Mol Biol
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J Mol Biol
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Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3.