Pamela Silver, PhD
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology, Harvard Medical School
Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors.
Authors: Authors: Gama-Carvalho M, Barbosa-Morais NL, Brodsky AS, Silver PA, Carmo-Fonseca M.
Genome Biol
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Genome Biol
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PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits.
Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae.
Authors: Authors: Beilharz T, Egan B, Silver PA, Hofmann K, Lithgow T.
J Biol Chem
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J Biol Chem
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Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions.
Authors: Authors: Tham WH, Wyithe JS, Ko Ferrigno P, Silver PA, Zakian VA.
Mol Cell
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Mol Cell
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Directing proteins to nucleus by fusion to nuclear localization signal tags.
The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B.
Authors: Authors: Kahana JA, Schlenstedt G, Evanchuk DM, Geiser JR, Hoyt MA, Silver PA.
Mol Biol Cell
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Mol Biol Cell
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RNA movement between the nucleus and the cytoplasm.
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.
Authors: Authors: Schlenstedt G, Saavedra C, Loeb JD, Cole CN, Silver PA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast.