Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Timing and checkpoints in the regulation of mitotic progression.
Authors: Authors: Meraldi P, Draviam VM, Sorger PK.
Dev Cell
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Image metrics in the statistical analysis of DNA microarray data.
Authors: Authors: Brown CS, Goodwin PC, Sorger PK.
Proc Natl Acad Sci U S A
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Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation.
Authors: Authors: Kaplan KB, Hyman AA, Sorger PK.
Cell
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Clathrin cubes: an extreme variant of the normal cage.
Authors: Authors: Sorger PK, Crowther RA, Finch JT, Pearse BM.
J Cell Biol
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Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.
Authors: Authors: Schauer NJ, Liu X, Magin RS, Doherty LM, Chan WC, Ficarro SB, Hu W, Roberts RM, Iacob RE, Stolte B, Giacomelli AO, Perera S, McKay K, Boswell SA, Weisberg EL, Ray A, Chauhan D, Dhe-Paganon S, Anderson KC, Griffin JD, Li J, Hahn WC, Sorger PK, Engen JR, Stegmaier K, Marto JA, Buhrlage SJ.
Sci Rep
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A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines.
Authors: Authors: Niepel M, Hafner M, Mills CE, Subramanian K, Williams EH, Chung M, Gaudio B, Barrette AM, Stern AD, Hu B, Korkola JE, Gray JW, Birtwistle MR, Heiser LM, Sorger PK.
Cell Syst
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A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.
Authors: Authors: Koch PD, Miller HR, Yu G, Tallarico JA, Sorger PK, Wang Y, Feng Y, Thomas JR, Ross NT, Mitchison T.
ACS Chem Biol
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Structure-guided development of covalent TAK1 inhibitors.
Authors: Authors: Tan L, Gurbani D, Weisberg EL, Hunter JC, Li L, Jones DS, Ficarro SB, Mowafy S, Tam CP, Rao S, Du G, Griffin JD, Sorger PK, Marto JA, Westover KD, Gray NS.
Bioorg Med Chem
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Failure analysis of clinical trials to test the amyloid hypothesis.
Authors: Authors: Hyman BT, Sorger P.
Ann Neurol
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Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.
Authors: Authors: Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R.
Nat Commun
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