Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data.
Authors: Authors: Janes KA, Kelly JR, Gaudet S, Albeck JG, Sorger PK, Lauffenburger DA.
J Comput Biol
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MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells.
Authors: Authors: Michel LS, Liberal V, Chatterjee A, Kirchwegger R, Pasche B, Gerald W, Dobles M, Sorger PK, Murty VV, Benezra R.
Nature
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Structure and function of kinetochores in budding yeast.
Authors: Authors: Hyman AA, Sorger PK.
Annu Rev Cell Dev Biol
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HSF1 phase transition mediates stress adaptation and cell fate decisions.
Authors: Authors: Gaglia G, Rashid R, Yapp C, Joshi GN, Li CG, Lindquist SL, Sarosiek KA, Whitesell L, Sorger PK, Santagata S.
Nat Cell Biol
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Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.
Authors: Authors: Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Tan L, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, Westover KD, Sorger PK, Gray NS.
Cell Chem Biol
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Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy.
Authors: Authors: Palmer AC, Sorger PK.
Cell
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Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation.
Authors: Authors: Jones DS, Jenney AP, Swantek JL, Burke JM, Lauffenburger DA, Sorger PK.
Nat Chem Biol
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Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis.
Authors: Authors: Kallenberger SM, Beaudouin J, Claus J, Fischer C, Sorger PK, Legewie S, Eils R.
Sci Signal
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Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays.
Authors: Authors: Gujral TS, Karp RL, Finski A, Chan M, Schwartz PE, MacBeath G, Sorger P.
Oncogene
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Adaptive informatics for multifactorial and high-content biological data.
Authors: Authors: Millard BL, Niepel M, Menden MP, Muhlich JL, Sorger PK.
Nat Methods
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