Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane.
Authors: Authors: Werbin JL, Avendaño MS, Becker V, Jungmann R, Yin P, Danuser G, Sorger PK.
Sci Rep
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Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method.
Authors: Authors: Lin JR, Fallahi-Sichani M, Sorger PK.
Nat Commun
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Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).
Authors: Authors: Paull EO, Carlin DE, Niepel M, Sorger PK, Haussler D, Stuart JM.
Bioinformatics
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A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins.
Authors: Authors: Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, Sorger PK, Macbeath G, Pötz O.
Sci Signal
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Classic and contemporary approaches to modeling biochemical reactions.
Authors: Authors: Chen WW, Niepel M, Sorger PK.
Genes Dev
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Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data.
Authors: Authors: Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK.
Mol Syst Biol
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Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour.
Authors: Authors: Aldridge BB, Haller G, Sorger PK, Lauffenburger DA.
Syst Biol (Stevenage)
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The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging.
Authors: Authors: Goldberg IG, Allan C, Burel JM, Creager D, Falconi A, Hochheiser H, Johnston J, Mellen J, Sorger PK, Swedlow JR.
Genome Biol
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Structure, function, and regulation of budding yeast kinetochores.
Authors: Authors: McAinsh AD, Tytell JD, Sorger PK.
Annu Rev Cell Dev Biol
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Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p.
Authors: Authors: Sassoon I, Severin FF, Andrews PD, Taba MR, Kaplan KB, Ashford AJ, Stark MJ, Sorger PK, Hyman AA.
Genes Dev
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