Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro.
Authors: Authors: Sorger PK, Severin FF, Hyman AA.
J Cell Biol
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Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine.
Authors: Authors: Du G, Rao S, Gurbani D, Henning NJ, Jiang J, Che J, Yang A, Ficarro SB, Marto JA, Aguirre AJ, Sorger PK, Westover KD, Zhang T, Gray NS.
J Med Chem
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Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries.
Authors: Authors: Moret N, Clark NA, Hafner M, Wang Y, Lounkine E, Medvedovic M, Wang J, Gray N, Jenkins J, Sorger PK.
Cell Chem Biol
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The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.
Authors: Authors: Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, Forlin M, Koleti A, Vidovic D, Chung C, Schürer SC, Vasiliauskas J, Pilarczyk M, Shamsaei B, Fazel M, Ren Y, Niu W, Clark NA, White S, Mahi N, Zhang L, Kouril M, Reichard JF, Sivaganesan S, Medvedovic M, Meller J, Koch RJ, Birtwistle MR, Iyengar R, Sobie EA, Azeloglu EU, Kaye J, Osterloh J, Haston K, Kalra J, Finkbiener S, Li J, Milani P, Adam M, Escalante-Chong R, Sachs K, Lenail A, Ramamoorthy D, Fraenkel E, Daigle G, Hussain U, Coye A, Rothstein J, Sareen D, Ornelas L, Banuelos M, Mandefro B, Ho R, Svendsen CN, Lim RG, Stocksdale J, Casale MS, Thompson TG, Wu J, Thompson LM, Dardov V, Venkatraman V, Matlock A, Van Eyk JE, Jaffe JD, Papanastasiou M, Subramanian A, Golub TR, Erickson SD, Fallahi-Sichani M, Hafner M, Gray NS, Lin JR, Mills CE, Muhlich JL, Niepel M, Shamu CE, Williams EH, Wrobel D, Sorger PK, Heiser LM, Gray JW, Korkola JE, Mills GB, LaBarge M, Feiler HS, Dane MA, Bucher E, Nederlof M, Sudar D, Gross S, Kilburn DF, Smith R, Devlin K, Margolis R, Derr L, Lee A, Pillai A.
Cell Syst
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L1000CDS2: LINCS L1000 characteristic direction signatures search engine.
Authors: Authors: Duan Q, Reid SP, Clark NR, Wang Z, Fernandez NF, Rouillard AD, Readhead B, Tritsch SR, Hodos R, Hafner M, Niepel M, Sorger PK, Dudley JT, Bavari S, Panchal RG, Ma'ayan A.
NPJ Syst Biol Appl
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Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states.
Authors: Authors: Koch Y, Wolf T, Sorger PK, Eils R, Brors B.
PLoS One
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Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors.
Authors: Authors: Bagci-Onder T, Agarwal A, Flusberg D, Wanningen S, Sorger P, Shah K.
Oncogene
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Molecular structures and interactions in the yeast kinetochore.
Authors: Authors: Cho US, Corbett KD, Al-Bassam J, Bellizzi JJ, De Wulf P, Espelin CW, Miranda JJ, Simons K, Wei RR, Sorger PK, Harrison SC.
Cold Spring Harb Symp Quant Biol
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Non-genetic cell-to-cell variability and the consequences for pharmacology.
Authors: Authors: Niepel M, Spencer SL, Sorger PK.
Curr Opin Chem Biol
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Phenotypic clustering of yeast mutants based on kinetochore microtubule dynamics.
Authors: Authors: Jaqaman K, Dorn JF, Marco E, Sorger PK, Danuser G.
Bioinformatics
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