Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer.
Authors: Authors: Rashid R, Gaglia G, Chen YA, Lin JR, Du Z, Maliga Z, Schapiro D, Yapp C, Muhlich J, Sokolov A, Sorger P, Santagata S.
Sci Data
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Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors.
Authors: Authors: Rapisuwon S, Izar B, Batenchuk C, Avila A, Mei S, Sorger P, Parks JM, Cooper SJ, Wagner D, Zeck JC, Charabaty AJ, Atkins MB.
J Immunother Cancer
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GRcalculator: an online tool for calculating and mining dose-response data.
Authors: Authors: Clark NA, Hafner M, Kouril M, Williams EH, Muhlich JL, Pilarczyk M, Niepel M, Sorger PK, Medvedovic M.
BMC Cancer
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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
Authors: Authors: Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jané-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA.
Science
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S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase.
Authors: Authors: Marco E, Dorn JF, Hsu PH, Jaqaman K, Sorger PK, Danuser G.
Cell
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Discovery of potent and selective covalent inhibitors of JNK.
Authors: Authors: Zhang T, Inesta-Vaquera F, Niepel M, Zhang J, Ficarro SB, Machleidt T, Xie T, Marto JA, Kim N, Sim T, Laughlin JD, Park H, LoGrasso PV, Patricelli M, Nomanbhoy TK, Sorger PK, Alessi DR, Gray NS.
Chem Biol
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New approaches to modeling complex biochemistry.
Authors: Authors: Bachman JA, Sorger P.
Nat Methods
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Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.
Authors: Authors: Aldridge BB, Saez-Rodriguez J, Muhlich JL, Sorger PK, Lauffenburger DA.
PLoS Comput Biol
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Collecting and organizing systematic sets of protein data.
Authors: Authors: Albeck JG, MacBeath G, White FM, Sorger PK, Lauffenburger DA, Gaudet S.
Nat Rev Mol Cell Biol
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Cell stimulus and lysis in a microfluidic device with segmented gas-liquid flow.
Authors: Authors: El-Ali J, Gaudet S, Günther A, Sorger PK, Jensen KF.
Anal Chem
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