Peter Sorger, PhD

Otto Krayer Professor of Systems Pharmacology, Harvard Medical School
Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII.
Authors: Authors: Espelin CW, Simons KT, Harrison SC, Sorger PK.
Mol Biol Cell
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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2.
Authors: Authors: Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK.
Cell
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Identification of essential components of the S. cerevisiae kinetochore.
Authors: Authors: Doheny KF, Sorger PK, Hyman AA, Tugendreich S, Spencer F, Hieter P.
Cell
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Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks.
Authors: Authors: Lyashenko E, Niepel M, Dixit PD, Lim SK, Sorger PK, Vitkup D.
Elife
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Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.
Authors: Authors: Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS.
Cell Chem Biol
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From word models to executable models of signaling networks using automated assembly.
Authors: Authors: Gyori BM, Bachman JA, Subramanian K, Muhlich JL, Galescu L, Sorger PK.
Mol Syst Biol
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Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway.
Authors: Authors: Shi T, Niepel M, McDermott JE, Gao Y, Nicora CD, Chrisler WB, Markillie LM, Petyuk VA, Smith RD, Rodland KD, Sorger PK, Qian WJ, Wiley HS.
Sci Signal
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BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response.
Authors: Authors: Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A.
Mol Cell
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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.
Authors: Authors: Lee MJ, Ye AS, Gardino AK, Heijink AM, Sorger PK, MacBeath G, Yaffe MB.
Cell
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Measuring and modeling apoptosis in single cells.
Authors: Authors: Spencer SL, Sorger PK.
Cell
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