Tim Mitchison

Timothy Mitchison, PhD

Hasib Sabbagh Professor of Systems Biology, Harvard Medical School

Tim Mitchison, PhD, received his BA in Biochemistry from Oxford University, England, in 1980, and his PhD from the University of California, San Francisco (UCSF), in Biochemistry and Biophysics in 1984, where he worked with Professor Marc Kirschner. At this time he discovered the dynamic instability of microtubules. Later he worked at the National Institute for Medical Research in London. In 1987 he returned to San Francisco to become an Assistant Professor at UCSF. In 1997 he moved to the Cell Biology Department at Harvard Medical School where he co-founded the Institute for Chemistry and Cell Biology.

Dr. Mitchison was a founding member of the HMS Department of Systems Biology, which started in 2004. He is currently Deputy Chair of the department, and Co-director of the Systems Biology PhD Program. He was elected a Fellow of the Royal Society in 1997, and member of the American Association of Arts and Sciences in 2008. In 2010 he served as President of the American Society of Cell Biology. And most recently in 2014 he became a member of the National Academy of Sciences.

Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix.
Authors: Authors: Kapoor TM, Mitchison TJ.
J Cell Biol
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Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules.
Authors: Authors: Oegema K, Wiese C, Martin OC, Milligan RA, Iwamatsu A, Mitchison TJ, Zheng Y.
J Cell Biol
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Preparation and characterization of caged fluorescein tubulin.
Authors: Authors: Desai A, Mitchison TJ.
Methods Enzymol
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Actin-based cell motility and cell locomotion.
Authors: Authors: Mitchison TJ, Cramer LP.
Cell
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The three faces of profilin.
Authors: Authors: Theriot JA, Mitchison TJ.
Cell
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Actin based motility on retraction fibers in mitotic PtK2 cells.
Authors: Authors: Mitchison TJ.
Cell Motil Cytoskeleton
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Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.
Authors: Authors: Mitchison TJ.
J Cell Biol
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Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro.
Authors: Authors: Vale RD, Schnapp BJ, Mitchison T, Steuer E, Reese TS, Sheetz MP.
Cell
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Colloid osmotic parameterization and measurement of subcellular crowding.
Authors: Authors: Mitchison TJ.
Mol Biol Cell
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Correction: 27 T ultra-high static magnetic field changes orientation and morphology of mitotic spindles in human cells.
Authors: Authors: Zhang L, Hou Y, Li Z, Ji X, Wang Z, Wang H, Tian X, Yu F, Yang Z, Pi L, Mitchison TJ, Lu Q, Zhang X.
Elife
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