Tim Mitchison

Timothy Mitchison, PhD

Hasib Sabbagh Professor of Systems Biology, Harvard Medical School

Tim Mitchison, PhD, received his BA in Biochemistry from Oxford University, England, in 1980, and his PhD from the University of California, San Francisco (UCSF), in Biochemistry and Biophysics in 1984, where he worked with Professor Marc Kirschner. At this time he discovered the dynamic instability of microtubules. Later he worked at the National Institute for Medical Research in London. In 1987 he returned to San Francisco to become an Assistant Professor at UCSF. In 1997 he moved to the Cell Biology Department at Harvard Medical School where he co-founded the Institute for Chemistry and Cell Biology.

Dr. Mitchison was a founding member of the HMS Department of Systems Biology, which started in 2004. He is currently Deputy Chair of the department, and Co-director of the Systems Biology PhD Program. He was elected a Fellow of the Royal Society in 1997, and member of the American Association of Arts and Sciences in 2008. In 2010 he served as President of the American Society of Cell Biology. And most recently in 2014 he became a member of the National Academy of Sciences.

Determining the position of the cell division plane.
Authors: Authors: Canman JC, Cameron LA, Maddox PS, Straight A, Tirnauer JS, Mitchison TJ, Fang G, Kapoor TM, Salmon ED.
Nature
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Cytoskeleton: what does GTP do for septins?
Authors: Authors: Mitchison TJ, Field CM.
Curr Biol
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Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP.
Authors: Authors: Taunton J, Rowning BA, Coughlin ML, Wu M, Moon RT, Mitchison TJ, Larabell CA.
J Cell Biol
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Tubulin and FtsZ structures: functional and therapeutic implications.
Authors: Authors: Desai A, Mitchison TJ.
Bioessays
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Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.
Authors: Authors: Welch MD, Iwamatsu A, Mitchison TJ.
Nature
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A new role for motor proteins as couplers to depolymerizing microtubules.
Authors: Authors: Desai A, Mitchison TJ.
J Cell Biol
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Microtubule-motor activity of a yeast centromere-binding protein complex.
Authors: Authors: Hyman AA, Middleton K, Centola M, Mitchison TJ, Carbon J.
Nature
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Mitotic spindle assembly by two different pathways in vitro.
Authors: Authors: Sawin KE, Mitchison TJ.
J Cell Biol
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Some thoughts on the partitioning of tubulin between monomer and polymer under conditions of dynamic instability.
Authors: Authors: Mitchison TJ, Kirschner MW.
Cell Biophys
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Centrosome development in early mouse embryos as defined by an autoantibody against pericentriolar material.
Authors: Authors: Calarco-Gillam PD, Siebert MC, Hubble R, Mitchison T, Kirschner M.
Cell
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