Tim Mitchison

Timothy Mitchison, PhD

Hasib Sabbagh Professor of Systems Biology, Harvard Medical School

Tim Mitchison, PhD, received his BA in Biochemistry from Oxford University, England, in 1980, and his PhD from the University of California, San Francisco (UCSF), in Biochemistry and Biophysics in 1984, where he worked with Professor Marc Kirschner. At this time he discovered the dynamic instability of microtubules. Later he worked at the National Institute for Medical Research in London. In 1987 he returned to San Francisco to become an Assistant Professor at UCSF. In 1997 he moved to the Cell Biology Department at Harvard Medical School where he co-founded the Institute for Chemistry and Cell Biology.

Dr. Mitchison was a founding member of the HMS Department of Systems Biology, which started in 2004. He is currently Deputy Chair of the department, and Co-director of the Systems Biology PhD Program. He was elected a Fellow of the Royal Society in 1997, and member of the American Association of Arts and Sciences in 2008. In 2010 he served as President of the American Society of Cell Biology. And most recently in 2014 he became a member of the National Academy of Sciences.

How does a millimeter-sized cell find its center?
Authors: Authors: Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ.
Cell Cycle
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Life and times of a cellular bleb.
Authors: Authors: Charras GT, Coughlin M, Mitchison TJ, Mahadevan L.
Biophys J
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Animal cytokinesis: from parts list to mechanisms.
Authors: Authors: Eggert US, Mitchison TJ, Field CM.
Annu Rev Biochem
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Multidimensional drug profiling by automated microscopy.
Authors: Authors: Perlman ZE, Slack MD, Feng Y, Mitchison TJ, Wu LF, Altschuler SJ.
Science
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Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.
Authors: Authors: Ohi R, Sapra T, Howard J, Mitchison TJ.
Mol Biol Cell
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The force-velocity relationship for the actin-based motility of Listeria monocytogenes.
Authors: Authors: McGrath JL, Eungdamrong NJ, Fisher CI, Peng F, Mahadevan L, Mitchison TJ, Kuo SC.
Curr Biol
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Psychosine, cytokinesis, and orphan receptors. Unexpected connections.
Authors: Authors: Mitchison TJ.
J Cell Biol
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Kin I kinesins are microtubule-destabilizing enzymes.
Authors: Authors: Desai A, Verma S, Mitchison TJ, Walczak CE.
Cell
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The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
Authors: Authors: Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ.
J Cell Biol
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Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.
Authors: Authors: Zheng Y, Wong ML, Alberts B, Mitchison T.
Nature
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