Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Cross-circulation and cell distribution kinetics in parabiotic mice.
Authors: Authors: Gibney BC, Chamoto K, Lee GS, Simpson DC, Miele LF, Tsuda A, Konerding MA, Wagers A, Mentzer SJ.
J Cell Physiol
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Muscling in: Uncovering the origins of rhabdomyosarcoma.
Authors: Authors: Hettmer S, Wagers AJ.
Nat Med
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Stem cell trafficking in tissue development, growth, and disease.
Authors: Authors: Laird DJ, von Andrian UH, Wagers AJ.
Cell
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Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates.
Authors: Authors: Passegué E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL.
J Exp Med
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Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells.
Authors: Authors: Sherwood RI, Christensen JL, Weissman IL, Wagers AJ.
Stem Cells
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Potent induction of FucT-VII in activated CD4+ T cells by TGF-b1 through a p38 MAP kinase-dependent pathway
Authors: Authors: Wagers AJ, Kansas GS
Journal of Immunology
Attenuation of PKCd enhances metabolic activity and promotes expansion of blood progenitors.
Authors: Authors: Rao TN, Gupta MK, Softic S, Wang LD, Jang YC, Thomou T, Bezy O, Kulkarni RN, Kahn CR, Wagers AJ.
EMBO J
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EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection.
Authors: Authors: Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG.
Cell
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Young, proliferative thymic epithelial cells engraft and function in aging thymuses.
Authors: Authors: Kim MJ, Miller CM, Shadrach JL, Wagers AJ, Serwold T.
J Immunol
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Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.
Authors: Authors: Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ.
Science
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