Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair.
Authors: Authors: Tabebordbar M, Wang ET, Wagers AJ.
Annu Rev Pathol
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Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat.
Authors: Authors: Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, Cerletti M, McDougall LE, Giorgadze N, Tchkonia T, Schrier D, Falb D, Kirkland JL, Wagers AJ, Tseng YH.
Proc Natl Acad Sci U S A
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Regulation and function of skeletal muscle stem cells.
Authors: Authors: Cerletti M, Shadrach JL, Jurga S, Sherwood R, Wagers AJ.
Cold Spring Harb Symp Quant Biol
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Incorporation of bone marrow-derived Flk-1-expressing CD34+ cells in the endothelium of tumor vessels in the mouse brain.
Authors: Authors: Santarelli JG, Udani V, Yung YC, Cheshier S, Wagers A, Brekken RA, Weissman I, Tse V.
Neurosurgery
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Hematopoietic stem cells
Authors: Authors: Domen J, Wagers A, Weissman IL
In Stem Cells: Scientific Progress and Future Research Directions
Cell fate determination from stem cells.
Authors: Authors: Wagers AJ, Christensen JL, Weissman IL.
Gene Ther
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P-selectin glycoprotein ligand-1 is essential for adhesion to P-selectin but not E-selectin in stably transfected hematopoietic cell lines.
Authors: Authors: Snapp KR, Wagers AJ, Craig R, Stoolman LM, Kansas GS.
Blood
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The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.
Authors: Authors: Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL.
Nat Commun
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Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting.
Authors: Authors: Maesner CC, Almada AE, Wagers AJ.
Skelet Muscle
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Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.
Authors: Authors: Hettmer S, Lin MM, Tchessalova D, Tortorici SJ, Castiglioni A, Desai T, Mao J, McMahon AP, Wagers AJ.
Exp Cell Res
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