Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

PKCd inhibition normalizes the wound-healing capacity of diabetic human fibroblasts.
Authors: Authors: Khamaisi M, Katagiri S, Keenan H, Park K, Maeda Y, Li Q, Qi W, Thomou T, Eschuk D, Tellechea A, Veves A, Huang C, Orgill DP, Wagers A, King GL.
J Clin Invest
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The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy.
Authors: Authors: Wang LD, Rao TN, Rowe RG, Nguyen PT, Sullivan JL, Pearson DS, Doulatov S, Wu L, Lindsley RC, Zhu H, DeAngelo DJ, Daley GQ, Wagers AJ.
Leukemia
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Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle.
Authors: Authors: Castiglioni A, Hettmer S, Lynes MD, Rao TN, Tchessalova D, Sinha I, Lee BT, Tseng YH, Wagers AJ.
Stem Cell Reports
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Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation.
Authors: Authors: Best JA, Blair DA, Knell J, Yang E, Mayya V, Doedens A, Dustin ML, Goldrath AW.
Nat Immunol
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Stem cells for skeletal muscle repair.
Authors: Authors: Shadrach JL, Wagers AJ.
Philos Trans R Soc Lond B Biol Sci
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Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.
Authors: Authors: Guibal FC, Alberich-Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, Zhang P, Santana-Lemos BA, Neuberg D, Wagers AJ, Rego EM, Tenen DG.
Blood
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Enhancing stem cell mobilization (pending)
Authors: Authors: Wagers AJ, Min IM
2007.
Hematopoietic cells maintain hematopoietic fates upon entering the brain.
Authors: Authors: Massengale M, Wagers AJ, Vogel H, Weissman IL.
J Exp Med
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Langerhans cells renew in the skin throughout life under steady-state conditions.
Authors: Authors: Merad M, Manz MG, Karsunky H, Wagers A, Peters W, Charo I, Weissman IL, Cyster JG, Engleman EG.
Nat Immunol
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IL-12 and IL-4 control T cell adhesion to endothelial selectins through opposite effects on FucT-VII gene expression
Authors: Authors: Wagers AJ, Waters CM, Stoolman LM, Kansas GS
Journal of Experimental Medicine