Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells.
Authors: Authors: Min IM, Pietramaggiori G, Kim FS, Passegué E, Stevenson KE, Wagers AJ.
Cell Stem Cell
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Identification of a cycling and radio-resistant dendritic cell population in mouse and human dermis: potential impact on graft versus host disease
Authors: Authors: Bogunovic M, Ginhoux F, Wagers A, Loubeau M, Isola LM, Lubrano L, Najfeld V, Phelps RG, Grosskreutz C, Scigliano E, Frenette P, Merad M
Journal of Experimental Medicine
Circulation and chemotaxis of fetal hematopoietic stem cells.
Authors: Authors: Christensen JL, Wright DE, Wagers AJ, Weissman IL.
PLoS Biol
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Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle.
Authors: Authors: Wright DE, Cheshier SH, Wagers AJ, Randall TD, Christensen JL, Weissman IL.
Blood
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The cis-Regulatory Atlas of the Mouse Immune System.
Authors: Authors: Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, Qi Y, Yu B, Robinette M, Kim KW, Wagers A, Rhoads A, Nutt SL, Brown BD, Mostafavi S, Buenrostro JD, Benoist C.
Cell
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Phosphoproteomic profiling of mouse primary HSPCs reveals new regulators of HSPC mobilization.
Authors: Authors: Wang LD, Ficarro SB, Hutchinson JN, Csepanyi-Komi R, Nguyen PT, Wisniewski E, Sullivan J, Hofmann O, Ligeti E, Marto JA, Wagers AJ.
Blood
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FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration.
Authors: Authors: Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, Almada AE, Mondino A, Wagers AJ, Manfredi AA, Rovere-Querini P.
PLoS One
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Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Authors: Authors: Hung CM, Calejman CM, Sanchez-Gurmaches J, Li H, Clish CB, Hettmer S, Wagers AJ, Guertin DA.
Cell Rep
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M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination.
Authors: Authors: Miron VE, Boyd A, Zhao JW, Yuen TJ, Ruckh JM, Shadrach JL, van Wijngaarden P, Wagers AJ, Williams A, Franklin RJM, Ffrench-Constant C.
Nat Neurosci
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Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.
Authors: Authors: Jiang X, Clark RA, Liu L, Wagers AJ, Fuhlbrigge RC, Kupper TS.
Nature
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