Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice.
Authors: Authors: Rask-Madsen C, Li Q, Freund B, Feather D, Abramov R, Wu IH, Chen K, Yamamoto-Hiraoka J, Goldenbogen J, Sotiropoulos KB, Clermont A, Geraldes P, Dall'Osso C, Wagers AJ, Huang PL, Rekhter M, Scalia R, Kahn CR, King GL.
Cell Metab
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Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations.
Authors: Authors: Jakubzick C, Tacke F, Ginhoux F, Wagers AJ, van Rooijen N, Mack M, Merad M, Randolph GJ.
J Immunol
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Differential expression of alpha2 integrin separates long-term and short-term reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ hematopoietic stem cells.
Authors: Authors: Wagers AJ, Weissman IL.
Stem Cells
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Plasticity of adult stem cells.
Authors: Authors: Wagers AJ, Weissman IL.
Cell
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Potent induction of alpha(1,3)-fucosyltransferase VII in activated CD4+ T cells by TGF-beta 1 through a p38 mitogen-activated protein kinase-dependent pathway.
Authors: Authors: Wagers AJ, Kansas GS.
J Immunol
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Methods of Isolation and Analysis of TREG Immune Infiltrates from Injured and Dystrophic Skeletal Muscle.
Authors: Authors: Burzyn D, Wagers A, Mathis D, Cerletti M.
Methods Mol Biol
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Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance.
Authors: Authors: Katagiri S, Park K, Maeda Y, Rao TN, Khamaisi M, Li Q, Yokomizo H, Mima A, Lancerotto L, Wagers A, Orgill DP, King GL.
Diabetes
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Engineering Escherichia coli into a protein delivery system for mammalian cells.
Authors: Authors: Reeves AZ, Spears WE, Du J, Tan KY, Wagers AJ, Lesser CF.
ACS Synth Biol
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Testosterone is essential for skeletal muscle growth in aged mice in a heterochronic parabiosis model.
Authors: Authors: Sinha I, Sinha-Hikim AP, Wagers AJ, Sinha-Hikim I.
Cell Tissue Res
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Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.
Authors: Authors: Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E.
Cell Stem Cell
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