Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues.
Authors: Authors: Massberg S, Schaerli P, Knezevic-Maramica I, Köllnberger M, Tubo N, Moseman EA, Huff IV, Junt T, Wagers AJ, Mazo IB, von Andrian UH.
Cell
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Simple and efficient isolation of hematopoietic stem cells from H2K-zFP transgenic mice.
Authors: Authors: Surdez D, Kunz B, Wagers AJ, Weissman IL, Terskikh AV.
Stem Cells
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Shifting Foci of Hematopoiesis during Reconstitution by Single Stem Cells
Authors: Authors: Cao Y*, Wagers AJ*, Beilhack A, Dusich J, Bachmann MH, Negrin RS, Weissman IL, Contag CH
*Equal contributors
Proceedings of the National Academy of Science USA
Regulation of alpha(1,3)-fucosyltransferase expression controls leukocyte adhesion to vascular selectins [dissertation]
Authors: Authors: Wagers AJ
1999.
Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group.
Authors: Authors: Teot LA, Schneider M, Thorner AR, Tian J, Chi YY, Ducar M, Lin L, Wlodarski M, Grier HE, Fletcher CDM, van Hummelen P, Skapek SX, Hawkins DS, Wagers AJ, Rodriguez-Galindo C, Hettmer S.
Cancer
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EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection.
Authors: Authors: Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG.
Cell
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Distinct malignant behaviors of mouse myogenic tumors induced by different oncogenetic lesions.
Authors: Authors: Hettmer S, Bronson RT, Wagers AJ.
Front Oncol
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Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma.
Authors: Authors: Kikuchi K, Hettmer S, Aslam MI, Michalek JE, Laub W, Wilky BA, Loeb DM, Rubin BP, Wagers AJ, Keller C.
PLoS Genet
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A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.
Authors: Authors: Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, DiBiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon LI.
Development
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Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function.
Authors: Authors: Jang YC, Sinha M, Cerletti M, Dall'Osso C, Wagers AJ.
Cold Spring Harb Symp Quant Biol
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