Amy Wagers, PhD
Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University
Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.
Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting.
Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.
Authors: Authors: Hettmer S, Lin MM, Tchessalova D, Tortorici SJ, Castiglioni A, Desai T, Mao J, McMahon AP, Wagers AJ.
Exp Cell Res
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Exp Cell Res
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Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Authors: Authors: Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Toro RD, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT.
Blood
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Blood
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New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism.
Induction of histiocytic sarcoma in mouse skeletal muscle.
Authors: Authors: Liu J, Hettmer S, Milsom MD, Hofmann I, Hua F, Miller C, Bronson RT, Wagers AJ.
PLoS One
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PLoS One
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Delivering on a promise. Interviewed by Kristie Nybo.
Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells.
Authors: Authors: Breault DT, Min IM, Carlone DL, Farilla LG, Ambruzs DM, Henderson DE, Algra S, Montgomery RK, Wagers AJ, Hole N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Ovulated oocytes in adult mice derive from non-circulating germ cells.
Authors: Authors: Eggan K, Jurga S, Gosden R, Min IM, Wagers AJ.
Nature
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Nature
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Incorporation of naive bone marrow derived cells into the vascular architecture of brain tumor.
Authors: Authors: Yung YC, Cheshier S, Santarelli JG, Huang Z, Wagers A, Weissman I, Tse V.
Microcirculation
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Microcirculation
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Changes in integrin expression are associated with altered homing properties of hematopoietic stem cells following mobilization by cyclophosphamide/ granulocyte colony-stimulating factor
Authors: Authors: Wagers AJ, Allsopp RA, Weissman, IL
Experimantal Hematology
Experimantal Hematology