Bruce Bean

Bruce Bean, PhD

Robert Winthrop Professor of Neurobiology, Harvard Medical School

Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.

Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties.
Authors: Authors: Zheng Y, Liu P, Bai L, Trimmer JS, Bean BP, Ginty DD.
Neuron
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Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons.
Authors: Authors: Liu PW, Bean BP.
J Neurosci
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Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies.
Authors: Authors: Cannon SC, Bean BP.
J Clin Invest
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FPL 64176 modification of Ca(V)1.2 L-type calcium channels: dissociation of effects on ionic current and gating current.
Authors: Authors: McDonough SI, Mori Y, Bean BP.
Biophys J
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Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons.
Authors: Authors: Raman IM, Bean BP.
J Neurosci
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Inhibition of P-type and N-type calcium channels by dopamine receptor antagonists.
Authors: Authors: Sah DW, Bean BP.
Mol Pharmacol
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Calcium channels. Gating for the physiologist.
Authors: Authors: Bean B.
Nature
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Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
Authors: Authors: Bean BP.
Proc Natl Acad Sci U S A
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The Role of CaV2.1 Channel Facilitation in Synaptic Facilitation.
Authors: Authors: Weyrer C, Turecek J, Niday Z, Liu PW, Nanou E, Catterall WA, Bean BP, Regehr WG.
Cell Rep
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Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.
Authors: Authors: Brenneis C, Kistner K, Puopolo M, Jo S, Roberson D, Sisignano M, Segal D, Cobos EJ, Wainger BJ, Labocha S, Ferreirós N, von Hehn C, Tran J, Geisslinger G, Reeh PW, Bean BP, Woolf CJ.
Br J Pharmacol
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