Bruce Bean, PhD
Robert Winthrop Professor of Neurobiology, Harvard Medical School
Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.
Sodium entry during action potentials of mammalian neurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons.
Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons.
Mibefradil inhibition of T-type calcium channels in cerebellar purkinje neurons.
Block of calcium channels in rat neurons by synthetic omega-Aga-IVA.
Dual control by ATP and acetylcholine of inwardly rectifying K+ channels in bovine atrial cells.
Maximal upstroke velocity as an index of available sodium conductance. Comparison of maximal upstroke velocity and voltage clamp measurements of sodium current in rabbit Purkinje fibers.
Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons.
Sidedness of carbamazepine accessibility to voltage-gated sodium channels.
Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents.
Authors: Authors: Binshtok AM, Gerner P, Oh SB, Puopolo M, Suzuki S, Roberson DP, Herbert T, Wang CF, Kim D, Chung G, Mitani AA, Wang GK, Bean BP, Woolf CJ.
Anesthesiology
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Anesthesiology
View full abstract on Pubmed
Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice.