Bruce Bean

Bruce Bean, PhD

Robert Winthrop Professor of Neurobiology, Harvard Medical School

Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.

Classes of calcium channels in vertebrate cells.
Authors: Authors: Bean BP.
Annu Rev Physiol
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Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels.
Authors: Authors: Wang W, Touhara KK, Weir K, Bean BP, MacKinnon R.
Elife
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Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review.
Authors: Authors: Roberson DP, Binshtok AM, Blasl F, Bean BP, Woolf CJ.
Br J Pharmacol
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Neurophysiology: stressful pacemaking.
Authors: Authors: Bean BP.
Nature
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Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons.
Authors: Authors: Taddese A, Bean BP.
Neuron
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Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC.
Authors: Authors: McDonough SI, Swartz KJ, Mintz IM, Boland LM, Bean BP.
J Neurosci
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Pharmacology and electrophysiology of ATP-activated ion channels.
Authors: Authors: Bean BP.
Trends Pharmacol Sci
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Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.
Authors: Authors: Huettner JE, Bean BP.
Proc Natl Acad Sci U S A
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Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons.
Authors: Authors: Kimm T, Khaliq ZM, Bean BP.
J Neurosci
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Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors.
Authors: Authors: Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ.
J Gen Physiol
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