Bruce Bean

Bruce Bean, PhD

Robert Winthrop Professor of Neurobiology, Harvard Medical School

Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.

Mibefradil inhibition of T-type calcium channels in cerebellar purkinje neurons.
Authors: Authors: McDonough SI, Bean BP.
Mol Pharmacol
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Block of calcium channels in rat neurons by synthetic omega-Aga-IVA.
Authors: Authors: Mintz IM, Bean BP.
Neuropharmacology
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Dual control by ATP and acetylcholine of inwardly rectifying K+ channels in bovine atrial cells.
Authors: Authors: Friel DD, Bean BP.
Pflugers Arch
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Maximal upstroke velocity as an index of available sodium conductance. Comparison of maximal upstroke velocity and voltage clamp measurements of sodium current in rabbit Purkinje fibers.
Authors: Authors: Cohen CJ, Bean BP, Tsien RW.
Circ Res
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Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons.
Authors: Authors: Hu W, Bean BP.
Neuron
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Sidedness of carbamazepine accessibility to voltage-gated sodium channels.
Authors: Authors: Jo S, Bean BP.
Mol Pharmacol
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Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents.
Authors: Authors: Binshtok AM, Gerner P, Oh SB, Puopolo M, Suzuki S, Roberson DP, Herbert T, Wang CF, Kim D, Chung G, Mitani AA, Wang GK, Bean BP, Woolf CJ.
Anesthesiology
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Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice.
Authors: Authors: Do MT, Bean BP.
J Neurophysiol
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Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors.
Authors: Authors: Sodickson DL, Bean BP.
J Neurosci
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Structure and properties of omega-agatoxin IVB, a new antagonist of P-type calcium channels.
Authors: Authors: Adams ME, Mintz IM, Reily MD, Thanabal V, Bean BP.
Mol Pharmacol
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