Bruce Bean

Bruce Bean, PhD

Robert Winthrop Professor of Neurobiology, Harvard Medical School

Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.

Selectively targeting pain in the trigeminal system.
Authors: Authors: Kim HY, Kim K, Li HY, Chung G, Park CK, Kim JS, Jung SJ, Lee MK, Ahn DK, Hwang SJ, Kang Y, Binshtok AM, Bean BP, Woolf CJ, Oh SB.
Pain
View full abstract on Pubmed
The molecular machinery of resurgent sodium current revealed.
Authors: Authors: Bean BP.
Neuron
View full abstract on Pubmed
beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.
Authors: Authors: Burgess DL, Biddlecome GH, McDonough SI, Diaz ME, Zilinski CA, Bean BP, Campbell KP, Noebels JL.
Mol Cell Neurosci
View full abstract on Pubmed
Taking the beta test.
Authors: Authors: Bean B.
Nature
View full abstract on Pubmed
Ca2+ channels in rat central and peripheral neurons: high-threshold current resistant to dihydropyridine blockers and omega-conotoxin.
Authors: Authors: Regan LJ, Sah DW, Bean BP.
Neuron
View full abstract on Pubmed
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.
Authors: Authors: Bean BP.
J Gen Physiol
View full abstract on Pubmed
Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties.
Authors: Authors: Zheng Y, Liu P, Bai L, Trimmer JS, Bean BP, Ginty DD.
Neuron
View full abstract on Pubmed
Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons.
Authors: Authors: Liu PW, Bean BP.
J Neurosci
View full abstract on Pubmed
Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies.
Authors: Authors: Cannon SC, Bean BP.
J Clin Invest
View full abstract on Pubmed
FPL 64176 modification of Ca(V)1.2 L-type calcium channels: dissociation of effects on ionic current and gating current.
Authors: Authors: McDonough SI, Mori Y, Bean BP.
Biophys J
View full abstract on Pubmed