David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner.
Authors: Authors: Su Z, Dziedzic SA, Hu D, Barrett VJ, Broekema N, Li W, Qian L, Jia N, Ofengeim D, Najafov A, Zhu H, Knipe DM, Yuan J.
Cell Death Differ
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History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains.
Authors: Authors: Colgrove RC, Liu X, Griffiths A, Raja P, Deluca NA, Newman RM, Coen DM, Knipe DM.
Virology
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HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesviruses.
Authors: Authors: Yan Z, Bryant KF, Gregory SM, Angelova M, Dreyfus DH, Zhao XZ, Coen DM, Burke TR, Knipe DM.
MBio
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Roles of the nuclear lamina in stable nuclear association and assembly of a herpesviral transactivator complex on viral immediate-early genes.
Authors: Authors: Silva L, Oh HS, Chang L, Yan Z, Triezenberg SJ, Knipe DM.
MBio
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Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters.
Authors: Authors: Cliffe AR, Garber DA, Knipe DM.
J Virol
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Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.
Authors: Authors: Melroe GT, Silva L, Schaffer PA, Knipe DM.
Virology
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Herpes simplex virus and toll-like receptors.
Authors: Authors: Finberg RW, Knipe DM, Kurt-Jones EA.
Viral Immunol
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Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2.
Authors: Authors: Zhao X, Deak E, Soderberg K, Linehan M, Spezzano D, Zhu J, Knipe DM, Iwasaki A.
J Exp Med
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“Virus-Host Cell Interactions” Chapter 7
Authors: Authors: Knipe DM, Samuel CE, Palese P
In: Fields Virology, Fourth Edition, D.M
Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease.
Authors: Authors: Da Costa XJ, Bourne N, Stanberry LR, Knipe DM.
Virology
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