David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
CNBP controls IL-12 gene transcription and Th1 immunity.
Authors: Authors: Chen Y, Sharma S, Assis PA, Jiang Z, Elling R, Olive AJ, Hang S, Bernier J, Huh JR, Sassetti CM, Knipe DM, Gazzinelli RT, Fitzgerald KA.
J Exp Med
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Protection from genital herpes disease, seroconversion and latent infection in a non-lethal murine genital infection model by immunization with an HSV-2 replication-defective mutant virus.
Authors: Authors: Diaz FM, Knipe DM.
Virology
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Interferon ?-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses.
Authors: Authors: Thompson MR, Sharma S, Atianand M, Jensen SB, Carpenter S, Knipe DM, Fitzgerald KA, Kurt-Jones EA.
J Biol Chem
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RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.
Authors: Authors: Barczak AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L, Borowsky ML, Onderdonk AB, Stanley SA, Kaur D, Bryant KF, Knipe DM, Sloutsky A, Hung DT.
Proc Natl Acad Sci U S A
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Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.
Authors: Authors: Hoshino Y, Pesnicak L, Dowdell KC, Burbelo PD, Knipe DM, Straus SE, Cohen JI.
J Infect Dis
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Palmitoylation of the cysteine-rich endodomain of the SARS-coronavirus spike glycoprotein is important for spike-mediated cell fusion.
Authors: Authors: Petit CM, Chouljenko VN, Iyer A, Colgrove R, Farzan M, Knipe DM, Kousoulas KG.
Virology
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Comparative efficacy and immunogenicity of replication-defective, recombinant glycoprotein, and DNA vaccines for herpes simplex virus 2 infections in mice and guinea pigs.
Authors: Authors: Hoshino Y, Dalai SK, Wang K, Pesnicak L, Lau TY, Knipe DM, Cohen JI, Straus SE.
J Virol
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Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion.
Authors: Authors: Kramer M, Riley J, Spoering A, Coen D, Knipe D.
Curr Eye Res
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“Herpes Simplex Viruses and Their Replication” Chapter 72
Authors: Authors: Roizman B, Knipe DM
In: Fields Virology, Fourth Edition, D.M
A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1.
Authors: Authors: Garber DA, Schaffer PA, Knipe DM.
J Virol
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