David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Viral replication is required for induction of ocular immunopathology by herpes simplex virus.
Authors: Authors: Babu JS, Thomas J, Kanangat S, Morrison LA, Knipe DM, Rouse BT.
J Virol
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Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
Authors: Authors: Kosz-Vnenchak M, Jacobson J, Coen DM, Knipe DM.
J Virol
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Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
Authors: Authors: Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM.
Proc Natl Acad Sci U S A
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An immunoassay for the study of DNA-binding activities of herpes simplex virus protein ICP8.
Authors: Authors: Lee CK, Knipe DM.
J Virol
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The potential significance of late herpes simplex virus functions expressed early in replication: The tale of a temperature-sensitive mutant
Authors: Authors: Roizman B, Batterson W, Knipe DM
Perspectives in Virology
Functions of cytoplasmic fibers in non-muscle cell motility
Authors: Authors: Goldman RD, Knipe DM
Cold Spring Harbor Symposium on Quantitative Biology
Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO).
Authors: Authors: Zmasek CM, Knipe DM, Pellett PE, Scheuermann RH.
Virology
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A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin.
Authors: Authors: Raja P, Lee JS, Pan D, Pesola JM, Coen DM, Knipe DM.
MBio
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Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.
Authors: Authors: Hill JM, Quenelle DC, Cardin RD, Vogel JL, Clement C, Bravo FJ, Foster TP, Bosch-Marce M, Raja P, Lee JS, Bernstein DI, Krause PR, Knipe DM, Kristie TM.
Sci Transl Med
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Decreasing herpes simplex viral infectivity in solution by surface-immobilized and suspended N,N-dodecyl,methyl-polyethylenimine.
Authors: Authors: Larson AM, Oh HS, Knipe DM, Klibanov AM.
Pharm Res
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