David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Simian TRIM5alpha proteins reduce replication of herpes simplex virus.
Authors: Authors: Reszka N, Zhou C, Song B, Sodroski JG, Knipe DM.
Virology
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Disruption of the U(L)41 gene in the herpes simplex virus 2 dl5-29 mutant increases its immunogenicity and protective capacity in a murine model of genital herpes.
Authors: Authors: Dudek T, Mathews LC, Knipe DM.
Virology
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Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion.
Authors: Authors: Petit CM, Melancon JM, Chouljenko VN, Colgrove R, Farzan M, Knipe DM, Kousoulas KG.
Virology
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Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells.
Authors: Authors: Wakimoto H, Johnson PR, Knipe DM, Chiocca EA.
Gene Ther
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Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection.
Authors: Authors: Verschoor A, Brockman MA, Knipe DM, Carroll MC.
J Immunol
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Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge.
Authors: Authors: Morrison LA, Da Costa XJ, Knipe DM.
Virology
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Viral replication is required for induction of ocular immunopathology by herpes simplex virus.
Authors: Authors: Babu JS, Thomas J, Kanangat S, Morrison LA, Knipe DM, Rouse BT.
J Virol
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Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
Authors: Authors: Kosz-Vnenchak M, Jacobson J, Coen DM, Knipe DM.
J Virol
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Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
Authors: Authors: Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM.
Proc Natl Acad Sci U S A
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An immunoassay for the study of DNA-binding activities of herpes simplex virus protein ICP8.
Authors: Authors: Lee CK, Knipe DM.
J Virol
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