David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
[Application of herpes simplex virus to HIV vaccine vector].
Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery.
Authors: Authors: Simpson-Holley M, Baines J, Roller R, Knipe DM.
J Virol
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J Virol
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Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme.
Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2.
Authors: Authors: Da Costa X, Kramer MF, Zhu J, Brockman MA, Knipe DM.
J Virol
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J Virol
View full abstract on Pubmed
A dominant mutant form of the herpes simplex virus ICP8 protein decreases viral late gene transcription.
Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection.
Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses.
Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4.
Nuclear localization of herpesvirus proteins: potential role for the cellular framework.
Maturation of viral proteins in cells infected with temperature-sensitive mutants of vesicular stomatitis virus.