David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation.
Authors: Authors: Peng T, Chanthaphavong RS, Sun S, Trigilio JA, Phasouk K, Jin L, Layton ED, Li AZ, Correnti CE, De van der Schueren W, Vazquez J, O'Day DR, Glass IA, Knipe DM, Wald A, Corey L, Zhu J.
J Exp Med
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Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters.
Authors: Authors: Oh HS, Traktman P, Knipe DM.
MBio
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Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.
Authors: Authors: Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM.
Proc Natl Acad Sci U S A
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Evidence for differences in immunologic and pathogenesis properties of herpes simplex virus 2 strains from the United States and South Africa.
Authors: Authors: Dudek TE, Torres-Lopez E, Crumpacker C, Knipe DM.
J Infect Dis
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Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.
Authors: Authors: Liu X, Fitzgerald K, Kurt-Jones E, Finberg R, Knipe DM.
Proc Natl Acad Sci U S A
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Replication-defective viruses as vaccines and vaccine vectors.
Authors: Authors: Dudek T, Knipe DM.
Virology
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Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis.
Authors: Authors: Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, Bronson R, Arnold MM, Knipe DM, Finberg RW.
Proc Natl Acad Sci U S A
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Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus.
Authors: Authors: Chen SH, Lee LY, Garber DA, Schaffer PA, Knipe DM, Coen DM.
J Virol
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Herpes simplex virus infection blocks events in the G1 phase of the cell cycle.
Authors: Authors: Song B, Liu JJ, Yeh KC, Knipe DM.
Virology
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Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.
Authors: Authors: Morrison LA, Knipe DM.
Virology
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