David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1.
Authors: Authors: Morrison LA, Knipe DM.
Virology
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“The replication of herpes simplex virus”
Authors: Authors: Knipe DM
In: Genital and Neonatal Herpes
Intragenic complementation of herpes simplex virus ICP8 DNA-binding protein mutants.
Authors: Authors: Gao M, Knipe DM.
J Virol
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Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Authors: Authors: Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA.
J Virol
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Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions.
Authors: Authors: Quinlan MP, Knipe DM.
Mol Cell Biol
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Molecular genetics of herpes simplex virus: the terminal a sequences of the L and S components are obligatorily identical and constitute a part of a structural gene mapping predominantly in the S component.
Authors: Authors: Knipe DM, Ruyechan WT, Honess RW, Roizman B.
Proc Natl Acad Sci U S A
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CNBP controls IL-12 gene transcription and Th1 immunity.
Authors: Authors: Chen Y, Sharma S, Assis PA, Jiang Z, Elling R, Olive AJ, Hang S, Bernier J, Huh JR, Sassetti CM, Knipe DM, Gazzinelli RT, Fitzgerald KA.
J Exp Med
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Protection from genital herpes disease, seroconversion and latent infection in a non-lethal murine genital infection model by immunization with an HSV-2 replication-defective mutant virus.
Authors: Authors: Diaz FM, Knipe DM.
Virology
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Interferon ?-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses.
Authors: Authors: Thompson MR, Sharma S, Atianand M, Jensen SB, Carpenter S, Knipe DM, Fitzgerald KA, Kurt-Jones EA.
J Biol Chem
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RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.
Authors: Authors: Barczak AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L, Borowsky ML, Onderdonk AB, Stanley SA, Kaur D, Bryant KF, Knipe DM, Sloutsky A, Hung DT.
Proc Natl Acad Sci U S A
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