David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses.
Authors: Authors: Hendricks GL, Velazquez L, Pham S, Qaisar N, Delaney JC, Viswanathan K, Albers L, Comolli JC, Shriver Z, Knipe DM, Kurt-Jones EA, Fygenson DK, Trevejo JM, Wang JP, Finberg RW.
Antiviral Res
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Antiviral Res
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CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2.
Authors: Authors: Soberman RJ, MacKay CR, Vaine CA, Ryan GB, Cerny AM, Thompson MR, Nikolic B, Primo V, Christmas P, Sheiffele P, Aronov L, Knipe DM, Kurt-Jones EA.
PLoS One
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PLoS One
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Construction and properties of a herpes simplex virus 2 dl5-29 vaccine candidate strain encoding an HSV-1 virion host shutoff protein.
Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs.
Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons.
Authors: Authors: LaVail JH, Tauscher AN, Hicks JW, Harrabi O, Melroe GT, Knipe DM.
J Virol
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J Virol
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Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures.
Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection.
The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.
Authors: Authors: Hann LE, Cook WJ, Uprichard SL, Knipe DM, Coen DM.
J Virol
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J Virol
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Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4.
Altered properties of the herpes simplex virus ICP8 DNA-binding protein in cells infected with ICP27 mutant viruses.