David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs.
Authors: Authors: Pan D, Li G, Morris-Love J, Qi S, Feng L, Mertens ME, Jurak I, Knipe DM, Coen DM.
MBio
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Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types.
Authors: Authors: Orzalli MH, Broekema NM, Knipe DM.
J Virol
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Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity.
Authors: Authors: Knipe DM.
Virology
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Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.
Authors: Authors: Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N.
Nat Immunol
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Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2.
Authors: Authors: Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM.
J Virol
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Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling.
Authors: Authors: Johnson KE, Song B, Knipe DM.
Virology
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Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection.
Authors: Authors: Simpson-Holley M, Colgrove RC, Nalepa G, Harper JW, Knipe DM.
J Virol
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Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.
Authors: Authors: Kramer MF, Cook WJ, Roth FP, Zhu J, Holman H, Knipe DM, Coen DM.
J Virol
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Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions.
Authors: Authors: Song B, Yeh KC, Liu J, Knipe DM.
Virology
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Comparison of the intranuclear distributions of herpes simplex virus proteins involved in various viral functions.
Authors: Authors: de Bruyn Kops A, Uprichard SL, Chen M, Knipe DM.
Virology
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