David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.
Authors: Authors: Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N.
Nat Immunol
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Nat Immunol
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Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2.
Authors: Authors: Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM.
J Virol
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J Virol
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Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling.
Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection.
Authors: Authors: Simpson-Holley M, Colgrove RC, Nalepa G, Harper JW, Knipe DM.
J Virol
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J Virol
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Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.
Authors: Authors: Kramer MF, Cook WJ, Roth FP, Zhu J, Holman H, Knipe DM, Coen DM.
J Virol
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J Virol
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Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions.
Comparison of the intranuclear distributions of herpes simplex virus proteins involved in various viral functions.
Authors: Authors: de Bruyn Kops A, Uprichard SL, Chen M, Knipe DM.
Virology
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Virology
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Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication.
Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia.
Authors: Authors: Jacobson JG, Ruffner KL, Kosz-Vnenchak M, Hwang CB, Wobbe KK, Knipe DM, Coen DM.
J Virol
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J Virol
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Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities.