David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1.
Authors: Authors: Rafield LF, Knipe DM.
J Virol
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Molecular genetics of herpes simplex virus: demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion.
Authors: Authors: Knipe DM, Ruyechan WT, Roizman B, Halliburton IW.
Proc Natl Acad Sci U S A
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Role of Herpes Simplex Virus 1 ?34.5 in the Regulation of IRF3 Signaling.
Authors: Authors: Manivanh R, Mehrbach J, Knipe DM, Leib DA.
J Virol
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Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus.
Authors: Authors: Angelova M, Ortiz-Meoz RF, Walker S, Knipe DM.
J Virol
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A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression.
Authors: Authors: Oh HS, Bryant KF, Nieland TJ, Mazumder A, Bagul M, Bathe M, Root DE, Knipe DM.
MBio
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Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia.
Authors: Authors: Kramer MF, Jurak I, Pesola JM, Boissel S, Knipe DM, Coen DM.
Virology
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The use of green fluorescent fusion proteins to monitor herpes simplex virus replication.
Authors: Authors: Taylor TJ, Knipe DM.
Methods Mol Biol
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Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Authors: Authors: Kaur A, Sanford HB, Garry D, Lang S, Klumpp SA, Watanabe D, Bronson RT, Lifson JD, Rosati M, Pavlakis GN, Felber BK, Knipe DM, Desrosiers RC.
Virology
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Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production.
Authors: Authors: Melroe GT, DeLuca NA, Knipe DM.
J Virol
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Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection.
Authors: Authors: Mann MA, Tyler KL, Knipe DM, Fields BN.
Virology
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