David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2.
Authors: Authors: Da Costa X, Kramer MF, Zhu J, Brockman MA, Knipe DM.
J Virol
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J Virol
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A dominant mutant form of the herpes simplex virus ICP8 protein decreases viral late gene transcription.
Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection.
Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses.
Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4.
Nuclear localization of herpesvirus proteins: potential role for the cellular framework.
Maturation of viral proteins in cells infected with temperature-sensitive mutants of vesicular stomatitis virus.
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation.
Authors: Authors: Peng T, Chanthaphavong RS, Sun S, Trigilio JA, Phasouk K, Jin L, Layton ED, Li AZ, Correnti CE, De van der Schueren W, Vazquez J, O'Day DR, Glass IA, Knipe DM, Wald A, Corey L, Zhu J.
J Exp Med
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J Exp Med
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Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters.
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.
Authors: Authors: Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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