David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Mechanisms of Host IFI16, PML, and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication.
Authors: Authors: Merkl PE, Orzalli MH, Knipe DM.
J Virol
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Combined cytotoxic activity of an infectious, but non-replicative herpes simplex virus type 1 and plasmacytoid dendritic cells against tumour cells.
Authors: Authors: Thomann S, Boscheinen JB, Vogel K, Knipe DM, DeLuca N, Gross S, Schuler-Thurner B, Schuster P, Schmidt B.
Immunology
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Cellular sensing of viral DNA and viral evasion mechanisms.
Authors: Authors: Orzalli MH, Knipe DM.
Annu Rev Microbiol
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Role of specific innate immune responses in herpes simplex virus infection of the central nervous system.
Authors: Authors: Wang JP, Bowen GN, Zhou S, Cerny A, Zacharia A, Knipe DM, Finberg RW, Kurt-Jones EA.
J Virol
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Genetic engineering of a modified herpes simplex virus 1 vaccine vector.
Authors: Authors: Liu X, Broberg E, Watanabe D, Dudek T, Deluca N, Knipe DM.
Vaccine
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ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.
Authors: Authors: Orlando JS, Balliet JW, Kushnir AS, Astor TL, Kosz-Vnenchak M, Rice SA, Knipe DM, Schaffer PA.
J Virol
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Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors.
Authors: Authors: Fontaine-Rodriguez EC, Taylor TJ, Olesky M, Knipe DM.
Virology
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Viral vaccines: Past, present and future
Authors: Authors: Knipe DM
Medicina Universitaria
Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model.
Authors: Authors: Jones CA, Taylor TJ, Knipe DM.
Virology
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Immunization with a replication-deficient mutant of herpes simplex virus type 1 (HSV-1) induces a CD8+ cytotoxic T-lymphocyte response and confers a level of protection comparable to that of wild-type HSV-1.
Authors: Authors: Brehm MA, Bonneau RH, Knipe DM, Tevethia SS.
J Virol
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