Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex
Authors: Authors: Han Chen, Ming F Lye, Christoph Gorgulla, Scott B Ficarro, Gregory D Cuny, David A Scott, Fan Wu, Paul W Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M Pesola, Sorin Draga, Jarrod A Marto, James M Hogle, Haribabu Arthanari, Donald M Coen
PLoS
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PLoS
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A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress.
Authors: Authors: Wilkie AR, Sharma M, Pesola JM, Ericsson M, Fernandez R, Coen DM.
J Virol
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J Virol
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Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity.
Authors: Authors: Chen H, Beardsley GP, Coen DM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.
Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.
Human cytomegalovirus protein kinase UL97 forms a complex with the tegument phosphoprotein pp65.
An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene.
High-frequency phenotypic reversion and pathogenicity of an acyclovir-resistant herpes simplex virus mutant.
Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments.
Importance of the herpes simplex virus UL24 gene for productive ganglionic infection in mice.
Authors: Authors: Jacobson JG, Chen SH, Cook WJ, Kramer MF, Coen DM.
Virology
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Virology
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