Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex
Authors: Authors: Han Chen, Ming F Lye, Christoph Gorgulla, Scott B Ficarro, Gregory D Cuny, David A Scott, Fan Wu, Paul W Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M Pesola, Sorin Draga, Jarrod A Marto, James M Hogle, Haribabu Arthanari, Donald M Coen
PLoS
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HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression.
Authors: Authors: Lawler JL, Coen DM.
J Gen Virol
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Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Authors: Authors: Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H.
Proc Natl Acad Sci U S A
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A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization.
Authors: Authors: Strang BL, Bender BJ, Sharma M, Pesola JM, Sanders RL, Spector DH, Coen DM.
J Virol
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Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2.
Authors: Authors: Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM.
J Virol
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Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis.
Authors: Authors: Jiang C, Hwang YT, Wang G, Randell JC, Coen DM, Hwang CB.
J Virol
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Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis.
Authors: Authors: Randell JC, Komazin G, Jiang C, Hwang CB, Coen DM.
J Virol
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Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion.
Authors: Authors: Kramer M, Riley J, Spoering A, Coen D, Knipe D.
Curr Eye Res
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Enzymatic amplification of DNA by PCR: standard procedures and optimization.
Authors: Authors: Kramer MF, Coen DM.
Curr Protoc Cell Biol
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The persistence of (HIV in) memory (T cells).
Authors: Authors: Coen DM.
Trends Microbiol
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