Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex
Authors: Authors: Han Chen, Ming F Lye, Christoph Gorgulla, Scott B Ficarro, Gregory D Cuny, David A Scott, Fan Wu, Paul W Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M Pesola, Sorin Draga, Jarrod A Marto, James M Hogle, Haribabu Arthanari, Donald M Coen
PLoS
View full abstract on Pubmed
Expression of herpes simplex virus 1 microRNAs in cell culture models of quiescent and latent infection.
Authors: Authors: Jurak I, Hackenberg M, Kim JY, Pesola JM, Everett RD, Preston CM, Wilson AC, Coen DM.
J Virol
View full abstract on Pubmed
Mammalian alphaherpesvirus miRNAs.
Authors: Authors: Jurak I, Griffiths A, Coen DM.
Biochim Biophys Acta
View full abstract on Pubmed
Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells.
Authors: Authors: Sinigalia E, Alvisi G, Mercorelli B, Coen DM, Pari GS, Jans DA, Ripalti A, Palù G, Loregian A.
J Virol
View full abstract on Pubmed
Low-level expression and reversion both contribute to reactivation of herpes simplex virus drug-resistant mutants with mutations on homopolymeric sequences in thymidine kinase.
Authors: Authors: Griffiths A, Link MA, Furness CL, Coen DM.
J Virol
View full abstract on Pubmed
The herpes simplex virus processivity factor, UL42, binds DNA as a monomer.
Authors: Authors: Randell JC, Coen DM.
J Mol Biol
View full abstract on Pubmed
Quantitation of rare DNAs by PCR.
Authors: Authors: Coen DM.
Curr Protoc Mol Biol
View full abstract on Pubmed
Herpes simplex virus processivity factor UL42 imparts increased DNA-binding specificity to the viral DNA polymerase and decreased dissociation from primer-template without reducing the elongation rate.
Authors: Authors: Weisshart K, Chow CS, Coen DM.
J Virol
View full abstract on Pubmed
Temporal regulation of herpes simplex virus type 1 UL24 mRNA expression via differential polyadenylation.
Authors: Authors: Cook WJ, Coen DM.
Virology
View full abstract on Pubmed
Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors.
Authors: Authors: Davar G, Kramer MF, Garber D, Roca AL, Andersen JK, Bebrin W, Coen DM, Kosz-Vnenchak M, Knipe DM, Breakefield XO, et al.
J Comp Neurol
View full abstract on Pubmed