Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Mutational analysis of DNA polymerase substrate recognition and subunit interactions using herpes simplex virus as prototype.
The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication.
Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses.
Effect of an amber mutation in the herpes simplex virus thymidine kinase gene on polypeptide synthesis and stability.
Authors: Authors: Irmiere AF, Manos MM, Jacobson JG, Gibbs JS, Coen DM.
Virology
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Virology
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Genetics of herpes simplex virus.
Authors: Authors: Schaffer PA, Weller SK, Pancake BA, Coen DM.
J Invest Dermatol
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J Invest Dermatol
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Mitochondrial genetics. VII. Allelism and mapping studies of ribosomal mutants resistant to chloramphenicol, erythromycin and spiramycin in S. cerevisiae.
Authors: Authors: Netter P, Petrochilo E, Slonimski PP, Bolotin-Fukuhara M, Coen D, Deutsch J, Dujon B.
Genetics
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Genetics
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Getting to and through the inner nuclear membrane during herpesvirus nuclear egress.
Authors: Authors: Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM.
Curr Opin Cell Biol
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Curr Opin Cell Biol
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Comparison of effects of inhibitors of viral and cellular protein kinases on human cytomegalovirus disruption of nuclear lamina and nuclear egress.
Antiviral drugs and antiviral drug resistance.
Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84.
Authors: Authors: Strang BL, Sinigalia E, Silva LA, Coen DM, Loregian A.
J Virol
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J Virol
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