Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Human cytomegalovirus UL50 and UL53 recruit viral protein kinase UL97, not protein kinase C, for disruption of nuclear lamina and nuclear egress in infected cells.
Authors: Authors: Sharma M, Kamil JP, Coughlin M, Reim NI, Coen DM.
J Virol
View full abstract on Pubmed
J Virol
View full abstract on Pubmed
HATs on for drug resistance.
The human cytomegalovirus UL44 C clamp wraps around DNA.
Authors: Authors: Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM.
Structure
View full abstract on Pubmed
Structure
View full abstract on Pubmed
Prediction and identification of herpes simplex virus 1-encoded microRNAs.
Authors: Authors: Cui C, Griffiths A, Li G, Silva LM, Kramer MF, Gaasterland T, Wang XJ, Coen DM.
J Virol
View full abstract on Pubmed
J Virol
View full abstract on Pubmed
ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells.
Linear diffusion on DNA despite high-affinity binding by a DNA polymerase processivity factor.
ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase.
Wheel keeps turning for antiviral combination chemotherapy.
CNS tumor therapy by attenuated herpes simplex viruses.
Authors: Authors: Mineta T, Markert JM, Takamiya Y, Coen DM, Rabkin SD, Martuza RL.
Gene Ther
View full abstract on Pubmed
Gene Ther
View full abstract on Pubmed
Isolation of foscarnet-resistant human cytomegalovirus patterns of resistance and sensitivity to other antiviral drugs.