Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Demonstration of circularization of herpes simplex virus DNA following infection using pulsed field gel electrophoresis.
Experimental therapy of human glioma by means of a genetically engineered virus mutant.
Authors: Authors: Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM.
Science
View full abstract on Pubmed
Science
View full abstract on Pubmed
A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells.
Authors: Authors: Jacobson JG, Leib DA, Goldstein DJ, Bogard CL, Schaffer PA, Weller SK, Coen DM.
Virology
View full abstract on Pubmed
Virology
View full abstract on Pubmed
Structural organization and unusual codon usage in the DNA polymerase gene from herpes simplex virus type 1.
Location of the single gene for the large subunit of ribulosebisphosphate carboxylase on the maize chloroplast chromosome.
Authors: Authors: Bedbrook JR, Coen DM, Beaton AR, Bogorad L, Rich A.
J Biol Chem
View full abstract on Pubmed
J Biol Chem
View full abstract on Pubmed
Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity.
Authors: Authors: Patel CD, Backes IM, Taylor SA, Jiang Y, Marchant A, Pesola JM, Coen DM, Knipe DM, Ackerman ME, Leib DA.
Sci Transl Med
View full abstract on Pubmed
Sci Transl Med
View full abstract on Pubmed
Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Authors: Authors: Lye MF, Sharma M, El Omari K, Filman DJ, Schuermann JP, Hogle JM, Coen DM.
EMBO J
View full abstract on Pubmed
EMBO J
View full abstract on Pubmed
Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA.
Priscilla Schaffer (1941-2009): a stalwart herpesvirologist.
The positively charged surface of herpes simplex virus UL42 mediates DNA binding.
Authors: Authors: Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM.
J Biol Chem
View full abstract on Pubmed
J Biol Chem
View full abstract on Pubmed