Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Acyclovir-resistant, pathogenic herpesviruses.
Authors: Authors: Coen DM.
Trends Microbiol
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Expanded spectrum of viral therapy in the treatment of nervous system tumors.
Authors: Authors: Markert JM, Coen DM, Malick A, Mineta T, Martuza RL.
J Neurosurg
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A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.
Authors: Authors: Digard P, Coen DM.
J Biol Chem
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Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
Authors: Authors: Coen DM, Irmiere AF, Jacobson JG, Kerns KM.
Virology
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Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.
Authors: Authors: Hall JD, Coen DM, Fisher BL, Weisslitz M, Randall S, Almy RE, Gelep PT, Schaffer PA.
Virology
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Mitochondrial genetics. VI. The petite mutation in Saccharomyces cerevisiae: interrelations between the loss of the p+ factor and the loss of the drug resistance mitochondrial genetic markers.
Authors: Authors: Deutsch J, Dujon B, Netter P, Petrochilo E, Slonimski PP, Bolotin-Fukuhara M, Coen D.
Genetics
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Mutations Inactivating Herpes Simplex Virus 1 MicroRNA miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia.
Authors: Authors: Pan D, Pesola JM, Li G, McCarron S, Coen DM.
J Virol
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A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency.
Authors: Authors: Pan D, Flores O, Umbach JL, Pesola JM, Bentley P, Rosato PC, Leib DA, Cullen BR, Coen DM.
Cell Host Microbe
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Herpes simplex virus 1 microRNAs expressed abundantly during latent infection are not essential for latency in mouse trigeminal ganglia.
Authors: Authors: Kramer MF, Jurak I, Pesola JM, Boissel S, Knipe DM, Coen DM.
Virology
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Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.
Authors: Authors: Hamirally S, Kamil JP, Ndassa-Colday YM, Lin AJ, Jahng WJ, Baek MC, Noton S, Silva LA, Simpson-Holley M, Knipe DM, Golan DE, Marto JA, Coen DM.
PLoS Pathog
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