Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism.
Authors: Authors: Loregian A, Sinigalia E, Mercorelli B, Palù G, Coen DM.
Nucleic Acids Res
View full abstract on Pubmed
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
Authors: Authors: Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J.
Science
View full abstract on Pubmed
The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress.
Authors: Authors: Krosky PM, Baek MC, Coen DM.
J Virol
View full abstract on Pubmed
Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation.
Authors: Authors: Chen SH, Garber DA, Schaffer PA, Knipe DM, Coen DM.
Virology
View full abstract on Pubmed
Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus.
Authors: Authors: Kramer MF, Chen SH, Knipe DM, Coen DM.
J Virol
View full abstract on Pubmed
Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase.
Authors: Authors: Jacobson J, Kramer M, Rozenberg F, Hu A, Coen DM.
Virology
View full abstract on Pubmed
A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.
Authors: Authors: Sullivan V, Biron KK, Talarico C, Stanat SC, Davis M, Pozzi LM, Coen DM.
Antimicrob Agents Chemother
View full abstract on Pubmed
P element regulatory products enhance zeste repression of a P[white duplicated] transgene in Drosophila melanogaster.
Authors: Authors: Coen D.
Genetics
View full abstract on Pubmed
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Authors: Authors: Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA.
J Virol
View full abstract on Pubmed
Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin.
Authors: Authors: Fleming HE, Coen DM.
Antimicrob Agents Chemother
View full abstract on Pubmed