Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Genetic analysis of temperature-sensitive mutants of HSV-1: the combined use of complementation and physical mapping for cistron assignment.
Authors: Authors: Weller SK, Aschman DP, Sacks WR, Coen DM, Schaffer PA.
Virology
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Mitochondrial nucleic acids in the petite colonie mutants: deletions and repetition of genes.
Authors: Authors: Faye G, Fukuhara H, Grandchamp C, Lazowska J, Michel F, Casey J, Getz GS, Locker J, Rabinowitz M, Bolotin-Fukuhara M, Coen D, Deutsch J, Dujon B, Netter P, Slonimski PP.
Biochimie
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High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions.
Authors: Authors: Polachek WS, Moshrif HF, Franti M, Coen DM, Sreenu VB, Strang BL.
J Virol
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Expression of herpes simplex virus 1 microRNAs in cell culture models of quiescent and latent infection.
Authors: Authors: Jurak I, Hackenberg M, Kim JY, Pesola JM, Everett RD, Preston CM, Wilson AC, Coen DM.
J Virol
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Mammalian alphaherpesvirus miRNAs.
Authors: Authors: Jurak I, Griffiths A, Coen DM.
Biochim Biophys Acta
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Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells.
Authors: Authors: Sinigalia E, Alvisi G, Mercorelli B, Coen DM, Pari GS, Jans DA, Ripalti A, Palù G, Loregian A.
J Virol
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Low-level expression and reversion both contribute to reactivation of herpes simplex virus drug-resistant mutants with mutations on homopolymeric sequences in thymidine kinase.
Authors: Authors: Griffiths A, Link MA, Furness CL, Coen DM.
J Virol
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The herpes simplex virus processivity factor, UL42, binds DNA as a monomer.
Authors: Authors: Randell JC, Coen DM.
J Mol Biol
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Quantitation of rare DNAs by PCR.
Authors: Authors: Coen DM.
Curr Protoc Mol Biol
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Herpes simplex virus processivity factor UL42 imparts increased DNA-binding specificity to the viral DNA polymerase and decreased dissociation from primer-template without reducing the elongation rate.
Authors: Authors: Weisshart K, Chow CS, Coen DM.
J Virol
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